[HTML][HTML] Powerful potential of polyfluoroalkyl-containing 4-arylhydrazinylidenepyrazol-3-ones for pharmaceuticals

YV Burgart, NA Elkina, EV Shchegolkov, OP Krasnykh… - Molecules, 2022 - mdpi.com
4-Arylhydrazinylidene-5-(polyfluoroalkyl) pyrazol-3-ones (4-AHPs) were found to be
obtained by the regiospecific cyclization of 2-arylhydrazinylidene-3-(polyfluoroalkyl)-3 …

New trifluoromethyl-containing (E)-N′-arylidene-[3-alkyl (aryl/heteroaryl)-4, 5-dihydro-1H-pyrazol-1-yl] carbohydrazides: Synthesis, crystal structure and antimicrobial …

HG Bonacorso, S Cavinatto, PT Campos… - Journal of Fluorine …, 2012 - Elsevier
A new series of twenty-one trifluoromethyl-containing (E)-N′-arylidene-1H-pyrazole-1-
carbohydrazides (4) was synthesized by the cyclocondensation reactions of six 3-alkyl …

Competitive routes to cyclizations of polyfluoroalkyl-containing 2-tolylhydrazinylidene-1, 3-diketones with 3-aminopyrazoles into bioactive pyrazoloazines

NA Elkina, YV Burgart, EV Shchegolkov… - Journal of Fluorine …, 2020 - Elsevier
The reaction of polyfluoroalkyl-containing 2-tolylhydrazinylidene-1, 3-diketones with 3-
aminopyrazoles depending on their structure can proceed as N, N-cyclization to form 5-R F …

[PDF][PDF] Synthesis of new trifluoromethyl-containing 1-(3, 5-dialkyl-4-hydroxybenzyl)-pyrazole and-pyrazol-5-one deriatives and their corresponding aroxyls

V Dinoiu, JM LÜ - Journal of the Serbian Chemical Society, 2006 - doiserbia.nb.rs
3, 5-Dialkyl-4-hydroxybenzylhydrazine 1 reacted with hexafluoroacetylacetone and
trifluoroacetylacetone yielding the pyrazoles 2 bearing trifluoromethyl and/or methyl …

Synthesis, antimicrobial, analgesic activity, and molecular docking studies of novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde …

ND Jayanna, HM Vagdevi, JC Dharshan… - Medicinal Chemistry …, 2013 - Springer
Abstract Condensation of 5, 7-dichloro-2-hydrazino-1, 3-benzoxazole 3 with different
aromatic acetophenones in methanol using catalytic amount of glacial acetic acid afforded …

[HTML][HTML] Studies on the Reactivity of (9-Methyl-5, 6-dihydronaphtho [1′, 2′: 4, 5]-thieno [2, 3-d] pyrimidin-11-yl) hydrazine Towards Some Reagents for Biological …

AE Rashad, AH Shamroukh… - Scientia …, 2010 - ncbi.nlm.nih.gov
Methyl-5, 6-dihydronaphtho [1′, 2′: 4, 5] thieno [2, 3-d] pyrimidin-11-yl) hydrazine (1) was
used as a precursor for preparation of some novel 1-(9-methyl-5, 6-dihydronaphtho [1 …

Reaction of hydrazinoquinolines with trifluoromethyl-β-diketones: structural and mechanistic studies

SP Singh, JK Kapoor, D Kumar… - Journal of fluorine …, 1997 - Elsevier
Reaction of 2-hydrazino-4-methylquinoline with a series of trifluoromethyl-β-diketones gives
3-substituted-5-hydroxy-1-(4-methylquinolin-2-yl)-5-trifluoromethyl-4, 5-dihydropyrazoles …

[引用][C] Synthesis and antimicrobial activity of pyrazole-4-carboxylic acid hydrazides and N-(4-pyrazoyl) hydrazones of aromatic and heteroaromatic aldehydes

VA Chornous, MK Bratenko, MV Vovk… - Pharmaceutical …, 2001 - Springer
Proceeding from the fact that some widely used antibacterial preparations (furacilin,
furazolidone, ftivazide) contain hydrazone groups, we decided to synthesize a series of …

5‐Alkoxy‐1‐aryl‐3‐polyfluoroalkylpyrazoles with Antinociceptive Activity: Partial Agonists of TRPV1 Ion Channels

OG Khudina, YV Burgart, NA Malkova… - …, 2023 - Wiley Online Library
Chemoselective O‐alkylation of 1‐aryl‐3‐polyfluoroalkylpyrazol‐5‐oles under basic
conditions resulted in a series of 5‐alkoxypyrazoles (26 derivatives). They showed an …

Applications of 2-arylhydrazononitriles in synthesis: Preparation of new indole containing 1, 2, 3-triazole, pyrazole and pyrazolo [1, 5-a] pyrimidine derivatives and …

H Behbehani, HM Ibrahim, S Makhseed… - European journal of …, 2011 - Elsevier
In this effort, 2-arylhdrazononitriles were used as key synthons for the preparation of wide
variety of new, uniquely substituted heterocyclic substances. In addition, the results of …