[PDF][PDF] The roles of polymers in mRNA delivery
Summary mRNA therapy, which possesses distinctive advantages over DNA and protein-
based therapies, has immense potential for diverse applications, including mRNA vaccines …
based therapies, has immense potential for diverse applications, including mRNA vaccines …
Polymer‐based mRNA delivery strategies for advanced therapies
W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
Nanoplatforms for mRNA therapeutics
C Meng, Z Chen, G Li, T Welte… - Advanced Therapeutics, 2021 - Wiley Online Library
Abstract mRNA‐based therapeutics are a unique class of drugs for treatment of human
diseases. Since in vitro transcribed mRNA molecules have relatively low stability and their …
diseases. Since in vitro transcribed mRNA molecules have relatively low stability and their …
Biomaterials for mRNA delivery
Messenger RNA (mRNA) has recently emerged with remarkable potential as an effective
alternative to DNA-based therapies because of several unique advantages. mRNA does not …
alternative to DNA-based therapies because of several unique advantages. mRNA does not …
Emerging mRNA technologies: delivery strategies and biomedical applications
The great success achieved by the two highly-effective messenger RNA (mRNA) vaccines
during the COVID-19 pandemic highlights the great potential of mRNA technology. Through …
during the COVID-19 pandemic highlights the great potential of mRNA technology. Through …
Nanoscale platforms for messenger RNA delivery
Messenger RNA (mRNA) has become a promising class of drugs for diverse therapeutic
applications in the past few years. A series of clinical trials are ongoing or will be initiated in …
applications in the past few years. A series of clinical trials are ongoing or will be initiated in …
mRNA delivery via non-viral carriers for biomedical applications
Q Shuai, F Zhu, M Zhao, Y Yan - International Journal of Pharmaceutics, 2021 - Elsevier
As an emerging new class of nucleic acid drugs, messenger RNA (mRNA) has huge
potential in immunotherapy, regenerative medicine, vaccine, and gene editing. Comparing …
potential in immunotherapy, regenerative medicine, vaccine, and gene editing. Comparing …
Advances in mRNA non-viral delivery approaches
ML Ibba, G Ciccone, CL Esposito, S Catuogno… - Advanced drug delivery …, 2021 - Elsevier
Messenger RNAs (mRNAs) present a great potential as therapeutics for the treatment and
prevention of a wide range of human pathologies, allowing for protein replacement …
prevention of a wide range of human pathologies, allowing for protein replacement …
Novel vectors and administrations for mRNA delivery
C Bai, C Wang, Y Lu - Small, 2023 - Wiley Online Library
Abstract mRNA therapy has shown great potential in infectious disease vaccines, cancer
immunotherapy, protein replacement therapy, gene editing, and other fields due to its central …
immunotherapy, protein replacement therapy, gene editing, and other fields due to its central …
Nanomaterials for mRNA‐based therapeutics: Challenges and opportunities
D Li, Q Liu, M Yang, H Xu, M Zhu… - Bioengineering & …, 2023 - Wiley Online Library
Messenger RNA (mRNA) holds great potential in developing immunotherapy, protein
replacement, and genome editing. In general, mRNA does not have the risk of being …
replacement, and genome editing. In general, mRNA does not have the risk of being …