Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease that results from the
accumulation of lipoproteinaceous material in the alveoli and alveolar macrophages due to …

Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the accumulation of
alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive …

Pulmonary alveolar proteinosis (PAP) is a rare respiratory syndrome characterised by the
accumulation of surfactant lipoproteins within the alveoli. According to various pathogenetic …

Understanding of the pathogenesis of PAP has greatly increased in the last decade; study
has brought better comprehension of lung biology and recognition of the critical role for GM …

Pulmonary alveolar proteinosis is a rare but potentially treatable disease, characterized by
impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous …

Pulmonary alveolar proteinosis is a rare syndrome characterized by intra-alveolar
accumulation of surfactant components and cellular debris, with minimal interstitial …

Pulmonary alveolar proteinosis is a rare clinical syndrome that was first described in 1958.
Subsequently, over 240 case reports and small series have described at least 410 cases in …

Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by the
accumulation of lipoproteinaceous material within the alveoli. Recent data suggest that …

In acquired pulmonary alveolar proteinosis, lipids and proteins accumulate within the alveoli
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …

Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterised by alveolar
accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte …