[HTML][HTML] DOAC‐Stop in lupus anticoagulant testing: direct oral anticoagulant interference removed in most samples

SA Baker, J Jin, C Pfaffroth, T Vu, JL Zehnder - Research and Practice in …, 2021 - Elsevier
Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic
option for patients at risk of thrombosis. DOACs interfere with clot‐based testing for the …

The effect of DOAC-Stop on lupus anticoagulant testing in plasma samples of venous thromboembolism patients receiving direct oral anticoagulants

M Ząbczyk, M Kopytek, J Natorska… - Clinical Chemistry and …, 2019 - degruyter.com
Abstract Background Direct oral anticoagulants (DOACs) cause false positive lupus
anticoagulant (LA) results. We assessed the impact of DOAC-Stop, reversing in vitro effects …

Neutralising rivaroxaban induced interference in laboratory testing for lupus anticoagulant (LA): a comparative study using DOAC Stop and andexanet alfa

EJ Favaloro, G Gilmore, S Arunachalam… - Thrombosis …, 2019 - Elsevier
Introduction Lupus anticoagulant (LA) investigation in patients on anticoagulant therapy is
problematic. Rivaroxaban in particular causes significant interference, prolonging both LA …

[HTML][HTML] Direct oral anticoagulant adsorption: impact on lupus anticoagulant testing—review of the literature and evaluation on spiked and patient samples

PM De Kesel, KMJ Devreese - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) interfere with lupus anticoagulant
(LAC) testing. DOAC‐Stop (D‐S) represents a preanalytical strategy to cope with this issue …

Performance characteristics of DOAC-Remove for neutralization of the effects of apixaban and rivaroxaban in lupus anticoagulant assays

JM Skaugen, C Sayre, AC Hassett… - American Journal of …, 2022 - academic.oup.com
Objectives This study established the performance characteristics of DOAC-Remove for
neutralization of the effects of rivaroxaban and apixaban in lupus anticoagulant (LAC) …

[HTML][HTML] Direct Oral Anticoagulant removal by a DOAC filter: Impact on lupus anticoagulant testing–Evaluation on spiked and patient samples

EA Linskens, P De Kesel, KMJ Devreese - Research and Practice in …, 2022 - Elsevier
Abstract Background DOAC Filter (DF) is a new device to overcome interference in lupus
anticoagulant (LAC) testing by direct oral anticoagulants (DOACs). Objectives We evaluated …

Effects of direct oral anticoagulants on lupus anticoagulant assays in a real-life setting

A Antovic, EM Norberg, M Berndtsson… - Thrombosis and …, 2017 - thieme-connect.com
Laboratory diagnosis of lupus anticoagulant (LA) is based on prolongation in at least one
coagulation assay (diluted Russell's viper venom time–dRVVT or activated partial …

Interference of DOACs in different DRVVT assays for diagnosis of lupus anticoagulants

T Flieder, M Weiser, TH Eller, M Dittrich… - Thrombosis …, 2018 - Elsevier
Objective Determination of lupus anticoagulants (LA) is an important, but still challenging
test in the diagnosis of antiphospholipid syndrome (APS). This is especially the case in …

Laboratory testing for lupus anticoagulant (LA) in patients taking direct oral anticoagulants (DOACs): potential for false positives and false negatives

EJ Favaloro, S Mohammed, J Curnow, L Pasalic - Pathology, 2019 - Elsevier
We and others have previously highlighted the potential problems with testing of lupus
anticoagulants (LA) in patients on anticoagulant therapy, including most recently as related …

Lupus-anticoagulant testing at NOAC trough levels

F Ratzinger, M Lang, S Belik… - Thrombosis and …, 2016 - thieme-connect.com
Non-vitamin K antagonist oral anticoagulants (NOAC), including rivaroxaban, apixaban or
dabigatran, regularly show relevant effects on coagulation tests, making the interpretation of …