[HTML][HTML] In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis

J Pijuan, C Barceló, DF Moreno, O Maiques… - Frontiers in cell and …, 2019 - frontiersin.org
Cell migration is a key procedure involved in many biological processes including
embryological development, tissue formation, immune defense or inflammation, and cancer …

In vitro cell migration and invasion assays

CR Justus, N Leffler, M Ruiz-Echevarria… - JoVE (Journal of …, 2014 - jove.com
Migration is a key property of live cells and critical for normal development, immune
response, and disease processes such as cancer metastasis and inflammation. Methods to …

Cell migration/invasion assays and their application in cancer drug discovery

SA Eccles, C Box, W Court - Biotechnology annual review, 2005 - Elsevier
Invasive capacity is the single most important trait that distinguishes benign from malignant
lesions. Tumour cells, during intravasation and extravasation of blood and lymphatic …

Established and novel methods of interrogating two-dimensional cell migration

WJ Ashby, A Zijlstra - Integrative Biology, 2012 - academic.oup.com
The regulation of cell motility is central to living systems. Consequently, cell migration
assays are some of the most frequently used in vitro assays. This article provides a …

Tumor spheroid-based migration assays for evaluation of therapeutic agents

M Vinci, C Box, M Zimmermann, SA Eccles - Target identification and …, 2013 - Springer
Cell migration is a key hallmark of malignant cells that contributes to the progression of
cancers from a primary, localized mass to an invasive and/or metastatic phenotype …

In vitro cell migration and invasion assays

N Kramer, A Walzl, C Unger, M Rosner… - … Research/Reviews in …, 2013 - Elsevier
Determining the migratory and invasive capacity of tumor and stromal cells and clarifying the
underlying mechanisms is most relevant for novel strategies in cancer diagnosis, prognosis …

[HTML][HTML] Current methods for studying metastatic potential of tumor cells

P Bouchalova, P Bouchal - Cancer cell international, 2022 - Springer
Cell migration and invasiveness significantly contribute to desirable physiological
processes, such as wound healing or embryogenesis, as well as to serious pathological …

[HTML][HTML] A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods

JC Yarrow, ZE Perlman, NJ Westwood, TJ Mitchison - BMC biotechnology, 2004 - Springer
Background Cell migration is a complex phenomenon that requires the coordination of
numerous cellular processes. Investigation of cell migration and its underlying biology is of …

Advances in wound-healing assays for probing collective cell migration

R Riahi, Y Yang, DD Zhang… - Journal of laboratory …, 2012 - journals.sagepub.com
Collective cell migration plays essential roles in a wide spectrum of biological processes,
such as embryogenesis, tissue regeneration, and cancer metastasis. Numerous wound …

[HTML][HTML] Sensitivity of edge detection methods for quantifying cell migration assays

KK Treloar, MJ Simpson - PloS one, 2013 - journals.plos.org
Quantitative imaging methods to analyze cell migration assays are not standardized. Here
we present a suite of two-dimensional barrier assays describing the collective spreading of …