The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens
Z Liu, S Huang, Y Zheng, T Zhou, L Hu, L Xiong… - Progress in retinal and …, 2023 - Elsevier
The crystalline lens is a transparent and refractive biconvex structure formed by lens
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …
[HTML][HTML] Lanosterol synthase mutations cause cholesterol deficiency–associated cataracts in the Shumiya cataract rat
M Mori, G Li, I Abe, J Nakayama, Z Guo… - The Journal of …, 2006 - Am Soc Clin Investig
The Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the
continuous occurrence of poorly differentiated epithelial cells at the bow area of the lens …
continuous occurrence of poorly differentiated epithelial cells at the bow area of the lens …
The ocular lens epithelium
SP Bhat - Bioscience reports, 2001 - portlandpress.com
An adult lens contains two easily discernible, morphologically distinct compartments, the
epithelium and the fiber-cell mass. The fiber-cell mass provides the lens with its functional …
epithelium and the fiber-cell mass. The fiber-cell mass provides the lens with its functional …
[HTML][HTML] Failure of oxysterols such as lanosterol to restore lens clarity from cataracts
DM Daszynski, P Santhoshkumar, AS Phadte… - Scientific reports, 2019 - nature.com
The paradigm that cataracts are irreversible and that vision from cataracts can only be
restored through surgery has recently been challenged by reports that oxysterols such as …
restored through surgery has recently been challenged by reports that oxysterols such as …
Degeneration and transdifferentiation of human lens epithelial cells in nuclear and anterior polar cataracts
CK Joo, EH Lee, JC Kim, YH Kim, JH Lee… - Journal of Cataract & …, 1999 - journals.lww.com
Purpose: To study the possible mechanisms of cataractogenesis by evaluating the
characteristics of cataractous lens epithelial cells (LECs) in different types of human cataract …
characteristics of cataractous lens epithelial cells (LECs) in different types of human cataract …
Structure of the lens and its associations with the visual quality
X Ruan, Z Liu, L Luo, Y Liu - BMJ Open Ophthalmology, 2020 - bmjophth.bmj.com
In humans, the lens is the organ with the ability to change morphology and refractive power,
designated as accommodation, to focus light from various distances and obtain clear retinal …
designated as accommodation, to focus light from various distances and obtain clear retinal …
Lens cells: more than meets the eye
FMD Tholozan, RA Quinlan - The international journal of biochemistry & …, 2007 - Elsevier
Lens cells originate from the head ectoderm and differentiate into an avascular organ
constituted from two contiguous cell subpopulations of very different morphology. Lens cells …
constituted from two contiguous cell subpopulations of very different morphology. Lens cells …
The ultrastructure of epithelial and fiber cells in the crystalline lens
JR Kuszak - International review of cytology, 1995 - Elsevier
Crystalline lenses are often simply described as inside-out stratified epithelial-like organs
composed of uniform (hexagonal cross-section profiles) crescent-like cells, arranged end-to …
composed of uniform (hexagonal cross-section profiles) crescent-like cells, arranged end-to …
The lens growth process
S Bassnett, H Šikić - Progress in retinal and eye research, 2017 - Elsevier
The factors that regulate the size of organs to ensure that they fit within an organism are not
well understood. A simple organ, the ocular lens serves as a useful model with which to …
well understood. A simple organ, the ocular lens serves as a useful model with which to …
Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation
M Medvedovic, CR Tomlinson, MK Call… - Molecular …, 2006 - ecommons.udayton.edu
Purpose: It has been shown that after extracapsular lens removal by anterior capsulotomy in
the mouse, the lens can be regenerated. However, as the capsular bag is filled with fibers …
the mouse, the lens can be regenerated. However, as the capsular bag is filled with fibers …