Background Natural killer (NK) cells are innate lymphoid cells that mediate antitumour and
antiviral responses. However, very little is known about how ageing influences human NK …

Background Understanding the host genetic architecture and viral immunity contributes to
the development of effective vaccines and therapeutics for controlling the COVID-19 …

Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …

Natural Killer (NK) cells are key innate effectors of antiviral immune response, and their
activity changes in ageing and severe acute respiratory syndrome coronavirus 2 (SARS …

Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …

Background The immune response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection in COVID-19 patients has been extensively investigated. However …

The determinants of severe COVID-19 in healthy adults are poorly understood, which limits
the opportunity for early intervention. We present a multiomic analysis using machine …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often causes
severe complications and even death. However, asymptomatic infection has also been …

The cell-mediated protective and pathogenic immune responses to SARS-CoV-2 infection
remain largely elusive. Here we identified 76 distinct cell subsets in the PBMC samples that …

The blood and immune system of coronavirus disease 2019 (COVID-19) infected patients
are dysfunctional, and numerous studies have been conducted to resolve their …