Deficiency of prebiotic fiber and insufficient signaling through gut metabolite-sensing receptors leads to cardiovascular disease
DM Kaye, WA Shihata, HA Jama, K Tsyganov… - Circulation, 2020 - Am Heart Assoc
Background: High blood pressure (BP) continues to be a major, poorly controlled but
modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet …
modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet …
Microbial peer pressure: the role of the gut microbiota in hypertension and its complications
There is increasing evidence of the influence of the gut microbiota on hypertension and its
complications, such as chronic kidney disease, stroke, heart failure, and myocardial …
complications, such as chronic kidney disease, stroke, heart failure, and myocardial …
High-fiber diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice
FZ Marques, E Nelson, PY Chu, D Horlock, A Fiedler… - Circulation, 2017 - Am Heart Assoc
Background: Dietary intake of fruit and vegetables is associated with lower incidence of
hypertension, but the mechanisms involved have not been elucidated. Here, we evaluated …
hypertension, but the mechanisms involved have not been elucidated. Here, we evaluated …
How dietary fibre, acting via the gut microbiome, lowers blood pressure
C Xu, FZ Marques - Current Hypertension Reports, 2022 - Springer
Abstract Purpose of Review To discuss the interplay behind how a high-fibre diet leads to
lower blood pressure (BP) via the gut microbiome. Recent Findings Compelling evidence …
lower blood pressure (BP) via the gut microbiome. Recent Findings Compelling evidence …
Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health
Abstract Purpose of this Review This review assesses the latest evidence linking short-chain
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …
Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction
E Catry, LB Bindels, A Tailleux, S Lestavel… - Gut, 2018 - gut.bmj.com
Objective To investigate the beneficial role of prebiotics on endothelial dysfunction, an early
key marker of cardiovascular diseases, in an original mouse model linking steatosis and …
key marker of cardiovascular diseases, in an original mouse model linking steatosis and …
Essential hypertension is associated with changes in gut microbial metabolic pathways: a multisite analysis of ambulatory blood pressure
Recent evidence supports a role for the gut microbiota in hypertension, but whether
ambulatory blood pressure is associated with gut microbiota and their metabolites remains …
ambulatory blood pressure is associated with gut microbiota and their metabolites remains …
Gut microbiota-derived short-chain fatty acids facilitate microbiota: host cross talk and modulate obesity and hypertension
HB Overby, JF Ferguson - Current hypertension reports, 2021 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the evidence
supporting a role of short-chain fatty acids (SCFAs) as messengers facilitating cross talk …
supporting a role of short-chain fatty acids (SCFAs) as messengers facilitating cross talk …
Probiotics and blood pressure: current insights
A Upadrasta, RS Madempudi - Integrated blood pressure control, 2016 - Taylor & Francis
Gut microbiota play a significant role in host metabolic processes, and recent metagenomic
surveys have revealed that they are involved in host immune modulation and influence host …
surveys have revealed that they are involved in host immune modulation and influence host …
Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41
N Natarajan, D Hori, S Flavahan… - Physiological …, 2016 - journals.physiology.org
Short chain fatty acid (SCFA) metabolites are byproducts of gut microbial metabolism that
are known to affect host physiology via host G protein-coupled receptor (GPCRs). We …
are known to affect host physiology via host G protein-coupled receptor (GPCRs). We …