The ever-growing use of inorganic nanoparticles (NPs) in biomedicine provides an exciting
approach to develop novel imaging and drug delivery systems, owing to the ease with which …

Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

The growing research interest in nanomedicine for the treatment of cancer and inflammatory-
related pathologies is yielding encouraging results. Unfortunately, enthusiasm is tempered …

While the blood vessel is seldom the target tissue, almost all nanomedicine will interact with
blood vessels and blood at some point of time along its life cycle in the human body …

The endothelium presents a formidable barrier for cancer nanomedicine, as the
intravenously introduced nanomedicine needs to leave the blood vessel at the tumor site …

Nanoparticles (NPs) comprised of nanoengineered complexes are providing new
opportunities for enabling targeted delivery of a range of therapeutics and combinations. A …

Endothelial leakiness or permeability directly determines the access of any
bionanotechnology to the target tissue site. Currently, cancer nanotechnology relies on …

Theranostic nanoparticles recently received great interest for uniting unique functions to
amplify therapeutic efficacy and reduce side effects. Despite the enhanced permeability and …

Brain cancer tumors cause disruption of the selective properties of vascular endothelia, even
causing disruptions in the very selective blood–brain barrier, which are collectively referred …