The impact of trophic and immunomodulatory factors on oligodendrocyte maturation: Potential treatments for encephalopathy of prematurity

JEG Vaes, MJV Brandt, N Wanders, MJNL Benders… - Glia, 2021 - Wiley Online Library
Encephalopathy of prematurity (EoP) is a major cause of morbidity in preterm neonates,
causing neurodevelopmental adversities that can lead to lifelong impairments. Preterm birth …

Impaired oligodendrocyte maturation in preterm infants: potential therapeutic targets

E Van Tilborg, CJ Heijnen, MJ Benders, F van Bel… - Progress in …, 2016 - Elsevier
Preterm birth is an evolving challenge in neonatal health care. Despite declining mortality
rates among extremely premature neonates, morbidity rates remain very high. Currently …

[HTML][HTML] Alteration of the oligodendrocyte lineage varies according to the systemic inflammatory stimulus in animal models that mimic the encephalopathy of …

G Favrais, C Bokobza, E Saliba, S Chalon… - Frontiers in …, 2022 - frontiersin.org
Preterm birth before the gestational age of 32 weeks is associated with the occurrence of
specific white matter damage (WMD) that can compromise the neurological outcome. These …

[HTML][HTML] Oligodendrocyte development and implication in perinatal white matter injury

M Motavaf, X Piao - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Perinatal white matter injury (WMI) is the most common brain injury in premature infants and
can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically …

Key roles of glial cells in the encephalopathy of prematurity

J Van Steenwinckel, C Bokobza, M Laforge, IK Shearer… - Glia, 2024 - Wiley Online Library
Across the globe, approximately one in 10 babies are born preterm, that is, before 37 weeks
of a typical 40 weeks of gestation. Up to 50% of preterm born infants develop brain injury …

Brain damage in preterm newborns: might enhancement of developmentally regulated endogenous protection open a door for prevention?

O Dammann, A Leviton - Pediatrics, 1999 - publications.aap.org
We present a two-component model of brain white matter damage in preterm neonates. The
insult component comprises infection and hypoxia-ischemia, which are both associated with …

The challenge of understanding cerebral white matter injury in the premature infant

CM Elitt, PA Rosenberg - Neuroscience, 2014 - Elsevier
White matter injury in the premature infant leads to motor and more commonly behavioral
and cognitive problems that are a tremendous burden to society. While there has been much …

The developing oligodendrocyte: key cellular target in brain injury in the premature infant

JJ Volpe, HC Kinney, FE Jensen… - International Journal of …, 2011 - Elsevier
Brain injury in the premature infant, a problem of enormous importance, is associated with a
high risk of neurodevelopmental disability. The major type of injury involves cerebral white …

Pathophysiology of glia in perinatal white matter injury

SA Back, PA Rosenberg - Glia, 2014 - Wiley Online Library
Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

[HTML][HTML] The potential of stem cell therapy to repair white matter injury in preterm infants: lessons learned from experimental models

JEG Vaes, MA Vink, CGM De Theije… - Frontiers in …, 2019 - frontiersin.org
Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm
born infant leading to life-long neurological impairments, including deficits in cognitive …