Dementia—a syndrome affecting human cognition—is a major public health concern given
to its rising prevalence worldwide. Though multiple research studies have analyzed …

Network models combined with gene expression studies have become useful tools for
studying complex diseases like Alzheimer's disease. We constructed a “Core” Alzheimer's …

Abstract Motivation: Neurodegenerative disorders (NDDs) are progressive and fatal
disorders, which are commonly characterized by the intracellular or extracellular presence of …

The large-scale datasets generated by gene sequencing, proteomics, and other
highthroughput experimental technologies are the bases for understanding life as a …

Background Recent developments have meant that network theory is making an important
contribution to the topological study of biological networks, such as protein-protein …

Dopamine receptors (DR) are one of the major neurotransmitter receptors present in human
brain. Malfunctioning of these receptors is well established to trigger many neurological and …

Alzheimer's disease (AD) generally results in neuronal loss due to protein dysfunction in
various brain regions. Genome-wide data have provided new opportunities to analyze the …

Background: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease
throughout the world. Most of the clinical symptoms of AD appear at a very later stage …

Background Systems biological approach of molecular connectivity map has reached to a
great interest to understand the gene functional similarities between the diseases. In this …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder that accounts for
numerous deaths worldwide. AD is the most common cause of dementia, characterized by …