Daidzein‐Based Amphiphilic Small Molecular Antimicrobial Peptidomimetics as Novel Antimicrobial Agents with Anti‐Biofilm Activity
A new series of daidzein‐based short peptidomimetic compounds were developed. In this
study, we incorporated an alkyl chain with different chain lengths as hydrophobic groups …
study, we incorporated an alkyl chain with different chain lengths as hydrophobic groups …
[HTML][HTML] Polyphenylglyoxamide-based amphiphilic small molecular peptidomimetics as antibacterial agents with anti-biofilm activity
The rapid emergence of drug-resistant bacteria is a major global health concern.
Antimicrobial peptides (AMPs) and peptidomimetics have arisen as a new class of …
Antimicrobial peptides (AMPs) and peptidomimetics have arisen as a new class of …
Smart Galactosidase‐Responsive Antimicrobial Dendron: Towards More Biocompatible Membrane‐Disruptive Agents
Z Shao, YD Xu, H Luo, K Hakobyan… - Macromolecular …, 2024 - Wiley Online Library
Antimicrobial resistance is a global healthcare challenge that urgently needs the
development of new therapeutic agents. Antimicrobial peptides and mimics thereof are …
development of new therapeutic agents. Antimicrobial peptides and mimics thereof are …
Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues
L Baldassarre, F Pinnen, C Cornacchia… - Journal of Peptide …, 2012 - Wiley Online Library
Worldwide efforts are underway to develop new antimicrobial agents against bacterial
resistance. To identify new compounds with a good antimicrobial profile, we designed and …
resistance. To identify new compounds with a good antimicrobial profile, we designed and …
Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity
M Ahn, P Gunasekaran, G Rajasekaran, EY Kim… - European journal of …, 2017 - Elsevier
In this study, we report on the first chemical synthesis of ultra-short pyrazole-arginine based
antimicrobial peptidomimetics derived from the newly synthesized N-alkyl/aryl pyrazole …
antimicrobial peptidomimetics derived from the newly synthesized N-alkyl/aryl pyrazole …
An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P. aeruginosa and negligible toxicity in vitro …
J Zhou, L Zhang, Y He, K Liu, F Zhang, H Zhang… - European Journal of …, 2021 - Elsevier
Due to the threat of escalating multi-drug resistant gram-negative bacteria to human health
and life, novel antimicrobial agents against gram-negative pathogens are urgently needed …
and life, novel antimicrobial agents against gram-negative pathogens are urgently needed …
Synthesis and biological evaluation of indole-based peptidomimetics as antibacterial agents against Gram-positive bacteria
Y Chen, H Li, J Liu, R Zhong, H Li, S Fang, S Liu… - European Journal of …, 2021 - Elsevier
The emergence of bacterial multidrug resistance and the lack of new antimicrobial agents
urgently demand the discovery and development of novel antibacterials that avoid bacterial …
urgently demand the discovery and development of novel antibacterials that avoid bacterial …
Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification
A Pini, A Giuliani, C Falciani, Y Runci… - Antimicrobial agents …, 2005 - Am Soc Microbiol
ABSTRACT A large 10-mer phage peptide library was panned against whole Escherichia
coli cells, and an antimicrobial peptide (QEKIRVRLSA) was selected. The peptide was …
coli cells, and an antimicrobial peptide (QEKIRVRLSA) was selected. The peptide was …
Antibacterial Mechanism of a Novel Peptide Dendrocin‑ZM1 Against Staphylococcus aureus by Increasing Membrane Permeability
SS Seyedjavadi, M Razzaghi-Abyaneh… - International Journal of …, 2023 - Springer
Staphylococcus aureus is a prevalent pathogen responsible for healthcare and community-
acquired infections, which lead to elevated rates of fatality and morbidity. With the …
acquired infections, which lead to elevated rates of fatality and morbidity. With the …
Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides
N Zhang, X Gu, D Song, P Zhang, N Zhang, W Chen… - Bioorganic …, 2022 - Elsevier
In recent years, bacterial resistance has risen sharply, which seriously endangers public
health due to the abuse of antibiotics and the lack of new antibiotics. Therefore, there is an …
health due to the abuse of antibiotics and the lack of new antibiotics. Therefore, there is an …