Mice born to mothers with gravida traumatic brain injury have distorted brain circuitry and altered immune responses

M Saber, JB Ortiz, LM Rojas Valencia, X Ma… - Journal of …, 2021 - liebertpub.com
Intimate partner violence (IPV) increases risk of traumatic brain injury (TBI). Physical
assaults increase in frequency and intensity during pregnancy. The consequences of TBI …

Multiparity differentially affects specific aspects of the acute neuroinflammatory response to traumatic brain injury in female mice

R Gilfarb, Z Tapp, E Lemanski, J Velasquez… - Neuroscience, 2023 - Elsevier
Pregnancy is associated with profound acute and long-term physiological changes, but the
effects of such changes on brain injury outcomes are unclear. Here, we examined the effects …

Neurobehavioral abnormalities in offspring of young adult male rats with a history of traumatic brain injury

LS Ju, J Zhu, TE Morey, N Gravenstein… - Journal of …, 2024 - liebertpub.com
Children of parents with traumatic brain injury (TBI) are more likely to develop psychiatric
disorders. This association is usually attributed to TBI-induced changes in parents' …

Mapping the impact of exposure to maternal immune activation on juvenile Wistar rat brain macro-and microstructure during early post-natal development

TC Wood, ME Edye, MK Harte… - Brain and …, 2019 - journals.sagepub.com
Maternal immune activation is consistently associated with elevated risk for multiple
psychiatric disorders in the affected offspring. Related to this, an important goal of our work …

Models of fetal brain injury, intrauterine inflammation, and preterm birth

I Burd, B Balakrishnan, S Kannan - American journal of …, 2012 - Wiley Online Library
Intrauterine infection and inflammation are known risk factors for brain damage in the
neonate irrespective of the gestational age. Infection‐induced maternal immune activation …

Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma

Y Golub, F Canneva, R Funke, S Frey… - Developmental …, 2016 - Wiley Online Library
Maternal posttraumatic stress disorder (PTSD) following trauma exposure during pregnancy
is associated with an increased risk of affective disorders in children. To investigate the …

“Females are not just 'protected'males”: Sex-specific vulnerabilities in placenta and brain after prenatal immune disruption

AE Braun, PA Carpentier, BA Babineau, AR Narayan… - eneuro, 2019 - eneuro.org
Current perceptions of genetic and environmental vulnerabilities in the developing fetus are
biased toward male outcomes. An argument is made that males are more vulnerable to …

Altered dendritic morphology in dorsolateral prefrontal cortex of nonhuman primates prenatally exposed to maternal immune activation

KL Hanson, RK Weir, AM Iosif, J Van de Water… - Brain, behavior, and …, 2023 - Elsevier
Women who contract a viral or bacterial infection during pregnancy have an increased risk
of giving birth to a child with a neurodevelopmental or psychiatric disorder. The effects of …

Correlates of brain injuries in women subjected to intimate partner violence: identifying the dangers and raising awareness

EM Valera, J Campbell, J Gill… - Journal of Aggression …, 2019 - Taylor & Francis
Awareness of the highly detrimental and long-term sequelae of brain injuries, and in
particular repetitive mild traumatic brain injuries (mTBIs/concussions), has been rapidly …

[HTML][HTML] Traumatic Brain Injury Effects on the Next Generation

DL Brody - Journal of Neurotrauma, 2024 - liebertpub.com
It is a pleasure to present a terrific lineup of articles in this issue of Journal of Neurotrauma.
I'd like to draw special attention to the article by Dr. Ju and colleagues entitled …