Induction of trained immunity by Bacille-Calmette-Guérin (BCG) vaccination mediates
beneficial heterologous effects, but the mechanisms underlying its persistence and …

Summary Bacillus Calmette-Guérin (BCG) vaccine is one of the most widely used vaccines
worldwide. In addition to protection against tuberculosis, BCG confers a degree of non …

The tuberculosis vaccine bacillus Calmette-Guérin (BCG) has heterologous beneficial
effects against non-related infections. The basis of these effects has been poorly explored in …

The dogma that adaptive immunity is the only arm of the immune response with memory
capacity has been recently challenged by several studies demonstrating evidence for …

The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the
ability to induce non-specific cross-protection against pathogens that might be unrelated to …

Vaccines have been traditionally developed with the presumption that they exert identical
immunogenicity regardless of target population and that they provide protection solely …

Abstract The Bacillus Calmette-Guérin (BCG) vaccine was discovered a century ago and
has since been clinically applicable. BCG can not only be used for the prevention of …

First administered to a human subject as a tuberculosis (TB) vaccine on July 18, 1921,
Bacillus Calmette-Guérin (BCG) has a long history of use for the prevention of TB and later …

Abstract Background Some strains of Bacillus Calmette–Guérin (BCG) vaccine not only
confer protection against disseminated forms of tuberculosis, but also reduce all-cause …

BCG vaccination can strengthen protection against pathogens through the induction of
epigenetic and metabolic reprogramming of innate immune cells, a process called trained …