Drug Addiction | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Drug addiction has afflicted mankind for centuries, yet the mechanisms by which particular
drugs lead to addiction, and the genetic factors that make some individuals particularly …

The purpose of this review is to illustrate the ways in which molecular neurobiological
investigations will contribute to an improved understanding of drug addiction and, ultimately …

Drug addiction is a chronically relapsing disorder that has been characterized by (1)
compulsion to seek and take the drug,(2) loss of control in limiting intake, and (3) emergence …

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems
in the brain that are responsible for drug addiction. Common neurobiological elements are …

Drug addiction is a brain disease--that's the modern view and it is fully expressed in this up-
to-date book. Among the many volumes on drugs written for lay readers, this one is unique …

RECENT SCIENTIFIC ADVANCES HAVE LED to a greater understanding of the
neurobiological processes that underlie drug abuse and addiction. These suggest that …

Although some aspects of drug addiction can occur relatively rapidly in response to acute
administration of a drug of abuse, most changes in brain function associated with addiction …

George F. Koob,* Pietro Paolo Sanna, and Floyd E. Bloom diction (Koob and Le Moal, 1997;
Koob et al., 1998). The underlying molecular and cellular changes that Department of …

Drug addiction presents as a chronic relapsing disorder characterized by persistent drug‐
seeking and drug‐taking behaviours. Given the significant detrimental effects of this disease …