Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …

Apolipoprotein B–containing lipoproteins include triglyceride-rich lipoproteins (chylomicrons
and their remnants, and very low-density lipoproteins and their remnants) and cholesterol …

Over the last century, many studies have demonstrated that low-density lipoprotein (LDL) is
a key risk factor of cardiovascular diseases (CVD) related to atherosclerosis. Thus, for these …

The iterative lipid impact on inflammation in atherosclerosi... : Current Opinion in Lipidology The
iterative lipid impact on inflammation in atherosclerosis : Current Opinion in Lipidology Log in or …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Cardiovascular disease is the largest cause of morbidity and premature mortality and its
major underlying pathology is atherosclerosis. Atherosclerosis commences with the …

Elevated plasma levels of low-density lipoprotein and generation of oxidized low-density
lipoprotein have been directly associated with the pathogenesis of atherosclerosis, and lipid …

Vascular areas of atherosclerotic development persist in a state of inflammation, and any
further inflammatory stimulus in the subintimal area elicits a proatherogenic response; this …

Firm epidemiological and clinical evidence shows that an increased LDL-cholesterol level is
proatherogenic and an increased HDL-cholesterol level is antiatherogenic. This is fully …

The central roles played by lipoproteins in atherosclerosis are well established. Increased
plasma concentrations of low-density lipoproteins (LDLs) and triglyceride-rich remnant …