Oleanolic acid (OA) is a natural triterpenoid with anticancer properties, but its hydrophobic
nature and poor aqueous solubility pose challenges in pharmaceutical formulation …

Oleanolic acid (OA) has shown promising antitumor activity. However, it is difficult to
formulate because of its poor water solubility and low bioavailability. In this study, self …

Objectives: Hepatocellular carcinoma is the third most common cause of cancer death.
Oleanolic acid (OA) is a natural triterpenoid, has many important biological actions …

Poly (d, l-lactide-co-glycolide)(PLGA) nanoparticles have attracted an enormous interest for
controlled drug delivery. Their clinical applications are, however, partly hindered by lack of …

Oleic acid (OA) is a kind of monounsaturated omega-3 fatty acid that abounds in plants and
animals which can induce apoptosis and has broad-spectrum inhibitory activity against a …

Despite the fact that various studies have investigated the clinical relevance of ellagic acid
(EA) as a naturally existing bioactive substance in cancer therapy, little has been reported …

Abstract Background and Objective: Role of dietary phenolic compounds in the modification
of pathophysiological conditions in cancer is immense. Thus, ellagic acid (EA), a natural …

We reported the development of multifunctional poly (lactic-co-glycolic acid)(PLGA)-lecithin-
polyethylene glycol (PEG) core-shell nanoparticles (NPs) that combined the beneficial …

The aim of this study was to obtain essential oil (LNEO) from the Laurus nobilis L. plant, and
to prepare LNEO-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) as an …

The effective delivery of oleanolic acid (OA) to the target site has several benefits in therapy
for different pathologies. However, the delivery of OA is challenging due to its poor aqueous …