Phylogenetic and functional analysis of the Cation Diffusion Facilitator (CDF) family: improved signature and prediction of substrate specificity

B Montanini, D Blaudez, S Jeandroz, D Sanders… - BMC genomics, 2007 - Springer
Abstract Background The Cation Diffusion Facilitator (CDF) family is a ubiquitous family of
heavy metal transporters. Much interest in this family has focused on implications for human …

[HTML][HTML] Cation diffusion facilitator family: structure and function

O Kolaj-Robin, D Russell, KA Hayes, JT Pembroke… - FEBS letters, 2015 - Elsevier
Abstract The Cation Diffusion Facilitators (CDFs) form a family of membrane-bound proteins
capable of transporting zinc and other heavy metal ions. Involved in metal …

A novel family of ubiquitous heavy metal ion transport proteins

IT Paulsen, MH Saier, Jr - The Journal of membrane biology, 1997 - Springer
We describe a novel diverse family of metal ion transporter (CDF) proteins (the cation
diffusion facilitator (CDF) family) with members occurring in both prokaryotes and …

New developments in the understanding of the cation diffusion facilitator family

CJ Haney, G Grass, S Franke… - Journal of Industrial …, 2005 - academic.oup.com
Cation diffusion facilitator (CDF) proteins are a phylogenetically ubiquitous family of
intermembrane transporters generally believed to play a role in the homeostasis of a wide …

Transition metal binding selectivity in proteins and its correlation with the phylogenomic classification of the cation diffusion facilitator protein family

S Barber-Zucker, B Shaanan, R Zarivach - Scientific reports, 2017 - nature.com
Divalent d-block metal cations (DDMCs), such as Fe, Zn and Mn, participate in many
biological processes. Understanding how specific DDMCs are transported to and within the …

Selective metal binding to a membrane-embedded aspartate in the Escherichia coli metal transporter YiiP (FieF)

Y Wei, D Fu - Journal of Biological Chemistry, 2005 - ASBMB
The cation diffusion facilitators (CDF) are a ubiquitous family of metal transporters that play
important roles in homeostasis of a wide range of divalent metal cations. Molecular identities …

The Chromosomally Encoded Cation Diffusion Facilitator Proteins DmeF and FieF from Wautersia metallidurans CH34 Are Transporters of Broad Metal Specificity

D Munkelt, G Grass, DH Nies - Journal of bacteriology, 2004 - Am Soc Microbiol
Genomic sequencing of the β-proteobacterium Wautersia (previously Ralstonia)
metallidurans CH34 revealed the presence of three genes encoding proteins of the cation …

Structure and evolution of the plant cation diffusion facilitator family of ion transporters

JL Gustin, MJ Zanis, DE Salt - BMC evolutionary biology, 2011 - Springer
Background Members of the cation diffusion facilitator (CDF) family are integral membrane
divalent cation transporters that transport metal ions out of the cytoplasm either into the …

Characteristics of Zinc Transport by Two Bacterial Cation Diffusion Facilitators from Ralstonia metallidurans CH34 and Escherichia coli

A Anton, A Weltrowski, CJ Haney, S Franke… - Journal of …, 2004 - Am Soc Microbiol
CzcD from Ralstonia metallidurans and ZitB from Escherichia coli are prototypes of bacterial
members of the cation diffusion facilitator (CDF) protein family. Expression of the czcD gene …

Metal selectivity determinants in a family of transition metal transporters

D Podar, J Scherer, Z Noordally, P Herzyk… - Journal of Biological …, 2012 - ASBMB
Metal tolerance proteins (MTPs) are plant members of the cation diffusion facilitator (CDF)
transporter family involved in cellular metal homeostasis. Members of the CDF family are …