[HTML][HTML] Image-guided surgery in patients with pancreatic cancer: first results of a clinical trial using SGM-101, a novel carcinoembryonic antigen-targeting, near …
CES Hoogstins, LSF Boogerd… - Annals of surgical …, 2018 - Springer
Background Near-infrared (NIR) fluorescence is a promising novel imaging technique that
can aid in intraoperative demarcation of pancreatic cancer (PDAC) and thus increase radical …
can aid in intraoperative demarcation of pancreatic cancer (PDAC) and thus increase radical …
Intraoperative pancreatic cancer detection using tumor-specific multimodality molecular imaging
WS Tummers, SE Miller, NT Teraphongphom… - Annals of surgical …, 2018 - Springer
Background Operative management of pancreatic ductal adenocarcinoma (PDAC) is
complicated by several key decisions during the procedure. Identification of metastatic …
complicated by several key decisions during the procedure. Identification of metastatic …
Preclinical evaluation of a novel CEA‐targeting near‐infrared fluorescent tracer delineating colorectal and pancreatic tumors
MC Boonstra, B Tolner, BE Schaafsma… - … journal of cancer, 2015 - Wiley Online Library
Surgery is the cornerstone of oncologic therapy with curative intent. However, identification
of tumor cells in the resection margins is difficult, resulting in nonradical resections …
of tumor cells in the resection margins is difficult, resulting in nonradical resections …
Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation
M McElroy, S Kaushal, GA Luiken, MA Talamini… - World journal of …, 2008 - Springer
Background Despite recent surgical advances, pancreatic cancer remains the fourth leading
cause of cancer-related death in the United States. This is due to inaccurate staging and …
cause of cancer-related death in the United States. This is due to inaccurate staging and …
[HTML][HTML] SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery
M Gutowski, B Framery, MC Boonstra, V Garambois… - Surgical oncology, 2017 - Elsevier
Purpose Fluorescence-guided surgery (FGS) provides surgeons with new opportunities to
improve real-time cancer nodule detection and tumor margin visualization. Currently, the …
improve real-time cancer nodule detection and tumor margin visualization. Currently, the …
Tumour-specific fluorescence-guided surgery for pancreatic cancer using panitumumab-IRDye800CW: a phase 1 single-centre, open-label, single-arm, dose …
Background Complete surgical resection remains the primary curative option for pancreatic
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
ductal adenocarcinoma, with positive margins in 30–70% of patients. In this study, we aimed …
Fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and …
CA Metildi, S Kaushal, M Pu, KA Messer… - Annals of surgical …, 2014 - Springer
Background We have developed a method of distinguishing normal tissue from pancreatic
cancer in vivo using fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) …
cancer in vivo using fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) …
Intraoperative near-infrared imaging can identify neoplasms and aid in real-time margin assessment during pancreatic resection
AD Newton, JD Predina, MH Shin… - Annals of …, 2019 - journals.lww.com
Objective: To determine if intraoperative near-infrared (NIR) imaging carries benefit in
resection of pancreatic neoplasms. Background: Resection of pancreatic malignancies is …
resection of pancreatic neoplasms. Background: Resection of pancreatic malignancies is …
Fluorophore-conjugated anti-CEA antibody for the intraoperative imaging of pancreatic and colorectal cancer
S Kaushal, MK McElroy, GA Luiken, MA Talamini… - Journal of …, 2008 - Elsevier
Introduction Colorectal and pancreatic cancers together comprise the third and fourth most
common causes of cancer-related death in the United States. In both of these cancers …
common causes of cancer-related death in the United States. In both of these cancers …
[HTML][HTML] Tumor-specific fluorescent antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer
HST Cao, S Kaushal, CA Metildi, RS Menen… - Hepato …, 2012 - ncbi.nlm.nih.gov
Results FL enabled more rapid and accurate identification and localization of primary tumors
and metastases than BL. Using BL took statistically significantly longer time than FL. More …
and metastases than BL. Using BL took statistically significantly longer time than FL. More …
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