DNA-based microarray studies in visceral leishmaniasis: identification of biomarkers for diagnostic, prognostic and drug target for treatment
Visceral leishmaniasis (VL) is one of the major infectious diseases affecting the poorest
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …
The contribution of DNA microarray technology to gene expression profiling in Leishmania spp.: A retrospective view
A Alonso, V Larraga, PJ Alcolea - Acta Tropica, 2018 - Elsevier
The first completed genome project of any living organism, excluding viruses, was of the
gammaproteobacteria Haemophilus influenzae in 1995. Until the last decade, genome …
gammaproteobacteria Haemophilus influenzae in 1995. Until the last decade, genome …
Molecular diagnosis of leishmaniasis
CAP Tavares, AP Fernandes… - Expert review of molecular …, 2003 - Taylor & Francis
This review describes the worldwide situation of visceral and tegumentary leishmaniasis
with an emphasis on diagnosis, including methods for the detection of antibodies, antigens …
with an emphasis on diagnosis, including methods for the detection of antibodies, antigens …
Global gene expression in Leishmania
The completion of the genomic sequences of many protozoan pathogens of humans,
including species of Leishmania, Trypanosoma and Plasmodium, provide new approaches …
including species of Leishmania, Trypanosoma and Plasmodium, provide new approaches …
Applications of molecular methods for Leishmania control
This article reviews the recent advances made in the field of human leishmaniasis. Special
emphasis is placed upon the application of various molecular tools for accurate and rapid …
emphasis is placed upon the application of various molecular tools for accurate and rapid …
Blood Transcriptional Profiling Reveals Immunological Signatures of Distinct States of Infection of Humans with Leishmania infantum
LG Gardinassi, GR Garcia, CHN Costa… - PLoS neglected …, 2016 - journals.plos.org
Visceral leishmaniasis (VL) can be lethal if untreated; however, the majority of human
infections with the etiological agents are asymptomatic. Using Illumina Bead Chip …
infections with the etiological agents are asymptomatic. Using Illumina Bead Chip …
Alteration of the serum biomarker profiles of visceral leishmaniasis during treatment
MS Duthie, J Guderian, A Vallur, A Bhatia… - European journal of …, 2014 - Springer
Until recently, chemotherapy for visceral leishmaniasis (VL; also known as kala-azar) was
severely limited by factors such as high cost, route of administration, generation of side …
severely limited by factors such as high cost, route of administration, generation of side …
Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays
Leishmania donovani causes visceral disease (kala-azar), a major health problem
throughout the tropics with 500 000 new cases every year. Leishmania differentiates from …
throughout the tropics with 500 000 new cases every year. Leishmania differentiates from …
Molecular diagnosis of visceral leishmaniasis
Visceral leishmaniasis (VL), a deadly parasitic disease, is a major public health concern
globally. Countries affected by VL have signed the London Declaration on Neglected …
globally. Countries affected by VL have signed the London Declaration on Neglected …
Multi-omic analyses of plasma cytokines, lipidomics, and transcriptomics distinguish treatment outcomes in cutaneous leishmaniasis
H Malta-Santos, KF Fukutani, CA Sorgi, ATL Queiroz… - Iscience, 2020 - cell.com
Leishmania braziliensis infection frequently results in cutaneous leishmaniasis (CL). An
increase in incidence of drug-resistant CL leading to treatment failure has been reported …
increase in incidence of drug-resistant CL leading to treatment failure has been reported …