Parental relatedness through time revealed by runs of homozygosity in ancient DNA

H Ringbauer, J Novembre, M Steinrücken - Nature communications, 2021 - nature.com
Parental relatedness of present-day humans varies substantially across the globe, but little
is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness …

KIN: a method to infer relatedness from low-coverage ancient DNA

D Popli, S Peyrégne, BM Peter - Genome Biology, 2023 - Springer
Genetic kinship of ancient individuals can provide insights into their culture and social
hierarchy, and is relevant for downstream genetic analyses. However, estimating …

A unified genealogy of modern and ancient genomes

AW Wohns, Y Wong, B Jeffery, A Akbari, S Mallick… - Science, 2022 - science.org
The sequencing of modern and ancient genomes from around the world has revolutionized
our understanding of human history and evolution. However, the problem of how best to …

Accurate detection of identity-by-descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick, I Olalde… - Nature Genetics, 2024 - nature.com
Long DNA segments shared between two individuals, known as identity-by-descent (IBD),
reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying …

Estimating genetic kin relationships in prehistoric populations

JM Monroy Kuhn, M Jakobsson, T Günther - PloS one, 2018 - journals.plos.org
Archaeogenomic research has proven to be a valuable tool to trace migrations of historic
and prehistoric individuals and groups, whereas relationships within a group or burial site …

Inferring population histories for ancient genomes using genome-wide genealogies

L Speidel, L Cassidy, RW Davies… - Molecular Biology …, 2021 - academic.oup.com
Ancient genomes anchor genealogies in directly observed historical genetic variation and
contextualize ancestral lineages with archaeological insights into their geography and …

Inferring demographic history from a spectrum of shared haplotype lengths

K Harris, R Nielsen - PLoS genetics, 2013 - journals.plos.org
There has been much recent excitement about the use of genetics to elucidate ancestral
history and demography. Whole genome data from humans and other species are revealing …

Dating genomic variants and shared ancestry in population-scale sequencing data

PK Albers, G McVean - PLoS biology, 2020 - journals.plos.org
The origin and fate of new mutations within species is the fundamental process underlying
evolution. However, while much attention has been focused on characterizing the presence …

The impact of whole-genome sequencing on the reconstruction of human population history

KR Veeramah, MF Hammer - Nature Reviews Genetics, 2014 - nature.com
Examining patterns of molecular genetic variation in both modern-day and ancient humans
has proved to be a powerful approach to learn about our origins. Rapid advances in DNA …

The strength of selection against Neanderthal introgression

I Juric, S Aeschbacher, G Coop - PLoS genetics, 2016 - journals.plos.org
Hybridization between humans and Neanderthals has resulted in a low level of Neanderthal
ancestry scattered across the genomes of many modern-day humans. After hybridization, on …