Increased procurement of thoracic donor organs after thyroid hormone therapy

D Novitzky, Z Mi, JF Collins, DKC Cooper - Seminars in Thoracic and …, 2015 - Elsevier
Hormonal therapy to the brain-dead organ donor can include thyroid hormone
(triiodothyronine [T 3] or levothyroxine [T 4]), antidiuretic hormone, corticosteroids, or insulin …

Thyroid hormone therapy in the management of 63,593 brain-dead organ donors: a retrospective analysis

D Novitzky, Z Mi, Q Sun, JF Collins… - Transplantation, 2014 - journals.lww.com
Background Hormonal therapy to the brain-dead potential organ donor can include thyroid
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …

Using thyroid hormone in brain‐dead donors to maximize the number of organs available for transplantation

A Salim, M Martin, C Brown, K Inaba… - Clinical …, 2007 - Wiley Online Library
The aggressive management of brain‐dead (cadaveric) organ donors has been shown to
increase organs available for transplantation. Some centers use hormone therapy with …

Thyroid hormone use during cardiac transplant organ procurement

LB Cooper, CA Milano, M Williams… - Clinical …, 2016 - Wiley Online Library
Background Acute hypothyroidism after brain death results in hemodynamic impairments
that limit availability of donor hearts. Thyroid hormone infusions can halt that process and …

A randomized trial of intravenous thyroxine for brain-dead organ donors with impaired cardiac function

R Dhar, E Stahlschmidt… - Progress in …, 2020 - journals.sagepub.com
Rationale: Brain death (BD) precipitates cardiac dysfunction impairing the ability to
transplant hearts from eligible organ donors. Retrospective studies have suggested that …

A randomized trial comparing triiodothyronine (T3) with thyroxine (T4) for hemodynamically unstable brain‐dead organ donors

R Dhar, E Stahlschmidt, Y Yan… - Clinical …, 2019 - Wiley Online Library
Rationale Brain‐dead (BD) organ donors frequently exhibit hemodynamic instability and/or
reversible cardiac dysfunction. Retrospective studies have suggested that thyroid hormone …

A systematic review and meta-analysis of clinical trials of thyroid hormone administration to brain dead potential organ donors

PS Macdonald, A Aneman, D Bhonagiri… - Critical care …, 2012 - journals.lww.com
Objectives: To review all published clinical studies of thyroid hormone administration to
brain-dead potential organ donors. Methods: A search of PubMed using multiple search …

[HTML][HTML] Intravenous levothyroxine for unstable brain-dead heart donors

R Dhar, GF Marklin, WD Klinkenberg… - … England Journal of …, 2023 - Mass Medical Soc
Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …

Thyroid hormone therapy and procurement of livers from brain-dead donors

D Novitzky, Z Mi, LA Videla, JF Collins… - Endocrine …, 2016 - Taylor & Francis
Hormonal therapy to brain-dead potential organ donors remains controversial. A
retrospective study was carried out of hormonal therapy on procurement of organs in 63,593 …

Trends in organ donor management: 2002 to 2012

DS Callahan, D Kim, S Bricker, A Neville… - Journal of the American …, 2014 - Elsevier
Background Refinements in donor management have resulted in increased numbers and
quality of grafts after neurologic death. We hypothesize that the increased use of hormone …