Early growth response-1 (Egr-1) is a Cys2-His2-type zinc-finger transcription factor. A broad
range of extracellular stimuli is capable of activating Egr-1, thus mediating growth …

The zinc finger protein early growth response 1 (Egr 1) is a transcriptional activator involved
in the regulation of growth and differentiation. We show here that a constitutive active mutant …

ABSTRACT Early growth response 1 (Egr-1) is a cellular transcription factor involved in
diverse biologic functions. Egr-1 has been associated with Epstein-Barr virus (EBV) …

Egr-1 is an immediate-early response gene induced transiently and ubiquitously by
mitogenic stimuli and also regulated in response to signals that initiate differentiation. The …

Early growth response factor 1: a pleiotropic mediator of inducible gene expression Page 1
Abstract The zinc-finger transcription factor, early growth response factor-1 (Egr-1) is an …

Early growth response‐1 (Egr‐1) is a master regulator and transcriptional sensor in vascular
dysfunction and disease. This article reviews recent developments in our understanding of …

Objective—The transcription factor early growth response (EGR)-1 has been implicated as a
key vascular phenotypic switch through its control of inducible transcription. EGR-1 …

We analyzed the G-actin-regulated transcriptome by gene expression analysis using
previously characterized actin-binding drugs. We found many known MAL/MRTF-dependent …

Activation of the transcription factor serum response factor (SRF) is dependent on Rho-
controlled changes in actin dynamics. We used pathway-specific inhibitors to compare the …

Serum response factor (SRF) is a highly conserved and widely expressed, single copy
transcription factor that theoretically binds up to 1,216 permutations of a 10-base pair cis …