Innate immunological pathways in COVID-19 pathogenesis
SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …
dysregulation of the innate immune system. This knowledge has emerged from the large …
[PDF][PDF] Innate immune and inflammatory responses to SARS-CoV-2: Implications for COVID-19
SA Lowery, A Sariol, S Perlman - Cell host & microbe, 2021 - cell.com
COVID-19 can result in severe disease characterized by significant immunopathology that is
spurred by an exuberant, yet dysregulated, innate immune response with a poor adaptive …
spurred by an exuberant, yet dysregulated, innate immune response with a poor adaptive …
[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
[PDF][PDF] Imbalanced host response to SARS-CoV-2 drives development of COVID-19
Viral pandemics, such as the one caused by SARS-CoV-2, pose an imminent threat to
humanity. Because of its recent emergence, there is a paucity of information regarding viral …
humanity. Because of its recent emergence, there is a paucity of information regarding viral …
[PDF][PDF] Immunology of COVID-19: current state of the science
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …
[HTML][HTML] Host cell-intrinsic innate immune recognition of SARS-CoV-2
EA Madden, MS Diamond - Current opinion in virology, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged at the end of
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …
[PDF][PDF] Heightened innate immune responses in the respiratory tract of COVID-19 patients
The outbreaks of 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
infection have posed a severe threat to global public health. It is unclear how the human …
infection have posed a severe threat to global public health. It is unclear how the human …
[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19
R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …
however, dysregulated innate immune responses can induce aberrant inflammation that is …
[HTML][HTML] Innate immunity: the first line of defense against SARS-CoV-2
MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
[HTML][HTML] SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”
BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …
immunity. Knowledge about this interplay can not only help us identify biological …