Nitric oxide in cell survival: a janus molecule

V Calabrese, C Cornelius, E Rizzarelli… - Antioxidants & Redox …, 2009 - liebertpub.com
Nitric oxide (NO), plays multiple roles in the nervous system. In addition to regulating
proliferation, survival and differentiation of neurons, NO is involved in synaptic activity …

Nitric oxide in health and disease of the nervous system

AB Knott, E Bossy-Wetzel - Antioxidants & redox signaling, 2009 - liebertpub.com
Nitric oxide (NO) is an important messenger molecule in a variety of physiological systems.
NO, a gas, is produced from L-arginine by different isoforms of nitric oxide synthase (NOS) …

Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation

A Contestabile, E Ciani - Neurochemistry international, 2004 - Elsevier
Nitric oxide (NO), an important cellular messenger, has been linked to both
neurodegenerative and neuroprotective actions. In the present review, we focus on recent …

Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes

V Calabrese, D Boyd-Kimball, G Scapagnini… - In vivo, 2004 - iv.iiarjournals.org
Nitric oxide and other reactive nitrogen species appear to play crucial roles in the brain such
as neuromodulation, neurotransmission and synaptic plasticity, but are also involved in …

Mechanisms of the antioxidant effects of nitric oxide

DA Wink, KM Miranda, MG Espey, RM Pluta… - … and redox signaling, 2001 - liebertpub.com
The Janus face of nitric oxide (NO) has prompted a debate as to whether NO plays a
deleterious or protective role in tissue injury. There are a number of reactive nitrogen oxide …

[HTML][HTML] Nitric oxide and cell death

MP Murphy - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1999 - Elsevier
Nitric oxide (NO) has several essential roles in mammals, but unregulated NO production
can cause cell death through oxidative stress, disrupted energy metabolism, DNA damage …

Regulation of programmed cell death in neuronal cells by nitric oxide

YC Kang, PK Kim, BM Choi, HT Chung, KS Ha… - In vivo, 2004 - iv.iiarjournals.org
Nitric oxide (NO), produced from L-arginine and molecular oxygen in a reaction catalyzed by
one of three NO synthase isoenzymes, can prevent or induce neuronal apoptosis depending …

The chemical biology of nitric oxide: implications in cellular signaling

DD Thomas, LA Ridnour, JS Isenberg… - Free Radical Biology …, 2008 - Elsevier
Nitric oxide (NO) has earned the reputation of being a signaling mediator with many diverse
and often opposing biological activities. The diversity in response to this simple diatomic …

NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance

V Calabrese, TE Bates, AMG Stella - Neurochemical research, 2000 - Springer
Nitric oxide and other reactive nitrogen species appear to play several crucial roles in the
brain. These include physiological processes such as neuromodulation, neurotransmission …

Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity

V Calabrese, C Mancuso, M Calvani… - Nature reviews …, 2007 - nature.com
At the end of the 1980s, it was clearly demonstrated that cells produce nitric oxide and that
this gaseous molecule is involved in the regulation of the cardiovascular, immune and …