SERS liquid biopsy profiling of serum for the diagnosis of kidney cancer

T Moisoiu, SD Iancu, D Burghelea, MP Dragomir… - Biomedicines, 2022 - mdpi.com
Renal cancer (RC) represents 3% of all cancers, with a 2% annual increase in incidence
worldwide, opening the discussion about the need for screening. However, no established …

Label-Free SERS of Urine Components: A Powerful Tool for Discriminating Renal Cell Carcinoma through Multivariate Analysis and Machine Learning Techniques

BA Buhas, V Toma, JB Beauval, I Andras… - International Journal of …, 2024 - mdpi.com
The advent of Surface-Enhanced Raman Scattering (SERS) has enabled the exploration
and detection of small molecules, particularly in biological fluids such as serum, blood …

High-Accuracy Renal Cell Carcinoma Discrimination through Label-Free SERS of Blood Serum and Multivariate Analysis

BA Buhas, V Toma, N Crisan, G Ploussard, TA Maghiar… - Biosensors, 2023 - mdpi.com
Renal cell carcinoma (RCC) represents the sixth most frequently diagnosed cancer in men
and is asymptomatic, being detected mostly incidentally. The apparition of symptoms …

Comparison of surface-enhanced Raman scattering properties of serum and urine for the detection of chronic kidney disease in patients

M Zong, L Zhou, Q Guan, D Lin, J Zhao… - Applied …, 2021 - journals.sagepub.com
Chronic kidney disease (CKD) affects more than 10% of the global population and is
associated with significant morbidity and mortality. In most cases, this disease is developed …

[HTML][HTML] Recent progress on liquid biopsy analysis using surface-enhanced Raman spectroscopy

Y Zhang, X Mi, X Tan, R Xiang - Theranostics, 2019 - ncbi.nlm.nih.gov
Traditional tissue biopsy is limited in understanding heterogeneity and dynamic evolution of
tumors. Instead, analyzing circulating cancer markers in various body fluids, commonly …

Raman spectral analysis of renal tissue: a novel application

EYH Huang, SC Chu, HG Chen… - Journal of Raman …, 2014 - Wiley Online Library
Renal cell carcinoma (RCC) accounts for 85% of all primary renal cancers. The definitive
diagnosis of RCC relies exclusively on the subjective pathological interpretation of the …

[HTML][HTML] Renal mass biopsy using Raman spectroscopy identifies malignant and benign renal tumors: potential for pre-operative diagnosis

Y Liu, Z Du, J Zhang, H Jiang - Oncotarget, 2017 - ncbi.nlm.nih.gov
The accuracy of renal mass biopsy to diagnose malignancy can be affected by multiple
factors. Here, we investigated the feasibility of Raman spectroscopy to distinguish malignant …

Unlocking Precision Medicine: Liquid Biopsy Advancements in Renal Cancer Detection and Monitoring

F Crocetto, A Falcone, BF Mirto, E Sicignano… - International Journal of …, 2024 - mdpi.com
Renal cell carcinoma (RCC) remains a formidable diagnostic challenge, especially in the
context of small renal masses. The quest for non-invasive screening tools and biomarkers …

Detecting urine metabolites of bladder cancer by surface-enhanced Raman spectroscopy

D Hu, X Xu, Z Zhao, C Li, Y Tian, Q Liu, B Shao… - … Acta Part A: Molecular …, 2021 - Elsevier
Aim Metabolites present in urine reflect the current phenotype of the cancer state. Surface-
enhanced Raman spectroscopy (SERS) can be used in urine supernatant or sediment to …

SERS-based liquid biopsy of gastrointestinal tumors using a portable Raman device operating in a clinical environment

L Avram, SD Iancu, A Stefancu, V Moisoiu… - Journal of Clinical …, 2020 - mdpi.com
Early diagnosis based on screening is recognized as one of the most efficient ways of
mitigating cancer-associated morbidity and mortality. Therefore, reliable but cost-effective …