CKD-induced wingless/Integration1 inhibitors and phosphorus cause the CKD–mineral and bone disorder
Y Fang, C Ginsberg, M Seifert, O Agapova… - Journal of the …, 2014 - journals.lww.com
In chronic kidney disease, vascular calcification, renal osteodystrophy, and phosphate
contribute substantially to cardiovascular risk and are components of CKD–mineral and …
contribute substantially to cardiovascular risk and are components of CKD–mineral and …
The chronic kidney disease—Mineral bone disorder (CKD-MBD): Advances in pathophysiology
KA Hruska, T Sugatani, O Agapova, Y Fang - Bone, 2017 - Elsevier
The causes of excess cardiovascular mortality associated with chronic kidney disease
(CKD) have been attributed in part to the CKD-mineral bone disorder syndrome (CKD-MBD) …
(CKD) have been attributed in part to the CKD-mineral bone disorder syndrome (CKD-MBD) …
Repression of osteocyte Wnt/β‐catenin signaling is an early event in the progression of renal osteodystrophy
Chronic kidney disease–mineral bone disorder (CKD‐MBD) is defined by abnormalities in
mineral and hormone metabolism, bone histomorphometric changes, and/or the presence of …
mineral and hormone metabolism, bone histomorphometric changes, and/or the presence of …
[HTML][HTML] Early chronic kidney disease–mineral bone disorder stimulates vascular calcification
Y Fang, C Ginsberg, T Sugatani, MC Monier-Faugere… - Kidney international, 2014 - Elsevier
The chronic kidney disease–mineral and bone disorder (CKD–MBD) syndrome is an
extremely important complication of kidney diseases. Here we tested whether CKD–MBD …
extremely important complication of kidney diseases. Here we tested whether CKD–MBD …
The connections between vascular calcification and bone health
JB Cannata-Andia, P Roman-Garcia… - Nephrology Dialysis …, 2011 - academic.oup.com
Vascular calcification, bone loss and increased fracture risk are age-associated disorders.
Several epidemiological studies have suggested a relationship between vascular …
Several epidemiological studies have suggested a relationship between vascular …
Pathophysiology of Chronic Kidney Disease Mineral Bone Disorder (CKD‐MBD)
KA Hruska, M Seifert - Primer on the Metabolic Bone Diseases …, 2013 - Wiley Online Library
This chapter talks about pathophysiology of chronic kidney disease mineral bone disorder
(CKD‐MBD). It discusses the pathogenetic factors such as fibroblast growth factor 23 …
(CKD‐MBD). It discusses the pathogenetic factors such as fibroblast growth factor 23 …
[HTML][HTML] Circulating levels of sclerostin but not DKK1 associate with laboratory parameters of CKD-MBD
GJ Behets, L Viaene, B Meijers, F Blocki… - PLoS …, 2017 - journals.plos.org
Introduction Mounting evidence indicates that a disturbed Wnt–β-catenin signaling may be
involved in the pathogenesis of chronic kidney disease-mineral and bone and mineral …
involved in the pathogenesis of chronic kidney disease-mineral and bone and mineral …
[HTML][HTML] SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling
J Voelkl, TTD Luong, R Tuffaha… - The Journal of …, 2018 - Am Soc Clin Investig
Medial vascular calcification, associated with enhanced mortality in chronic kidney disease
(CKD), is fostered by osteo-/chondrogenic transdifferentiation of vascular smooth muscle …
(CKD), is fostered by osteo-/chondrogenic transdifferentiation of vascular smooth muscle …
Chronic hyperphosphatemia and vascular calcification are reduced by stable delivery of soluble klotho
JM Hum, LM O'Bryan, AK Tatiparthi… - Journal of the …, 2017 - journals.lww.com
Abstract αKlotho (αKL) regulates mineral metabolism, and diseases associated with αKL
deficiency are characterized by hyperphosphatemia and vascular calcification (VC). αKL is …
deficiency are characterized by hyperphosphatemia and vascular calcification (VC). αKL is …
[HTML][HTML] Sclerostin and DKK1: new players in renal bone and vascular disease
P Evenepoel, P D'haese, V Brandenburg - Kidney international, 2015 - Elsevier
For more than a decade, the Wnt–β-catenin pathway has been the focus of intense basic
and clinical research in the bone field because of its importance in skeletal development …
and clinical research in the bone field because of its importance in skeletal development …