Biotechnological processes are crucial to the development of any economy striving to
ensure a relevant position in future markets. The cultivation of microorganisms in bioreactors …

New reactor concepts as multi-parallel screening systems or disposable bioreactor systems
for decentralized and reproducible production increase the need for new and easy …

The performance of an activated sludge reactor can be significantly enhanced through use
of continuous and real-time process-state monitoring, which avoids the need to sample for …

The use of spectroscopic sensors for bioprocess monitoring is a powerful tool within the
process analytical technology (PAT) initiative of the US Food and Drug Administration …

Optical sensor systems are of increasing interest in bioprocess monitoring, because they are
very sensitive, specific and noninvasive. Recent developments in optical-density probes, in …

Biological processes based on aerobic and anaerobic technologies have been continuously
developed to wastewater treatment and are currently routinely employed to reduce the …

On-line sensors for the detection of crucial process parameters are desirable for the
monitoring, control and automation of processes in the biotechnology, food and pharma …

One of the major aims of bioprocess engineering is the real-time monitoring of important
process variables. This is the basis of precise process control and is essential for high …

The application of near infrared spectroscopy in bioprocessing has been limited by its
dependence on calibrations derived from single bioreactor at a given time. Here, we …

The production process of an active pharmaceutical ingredient (API) by fermentation in an
industrial environment was analysed using process analytical technologies. The Food and …