Simple Summary Cancer metastasis is often associated with a dismal prognosis for the
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …

Cancer associated fibroblasts (CAFs) is one of the most crucial components of the tumor
microenvironment which promotes the growth and invasion of cancer cells by various …

Cancer-associated fibroblasts (CAFs) are activated fibroblasts in the tumor
microenvironment. They are one of the most prominent cell types in the stroma and produce …

The tumor microenvironment (TME) is populated by abundant cancer-associated fibroblasts
(CAFs) that radically influence the disease progression across many cancers, including the …

Despite centuries since the discovery and study of cancer, cancer is still a lethal and
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …

The ability of cancer cells to move out of the primary tumor and disseminate through the
circulation to form metastases is one of the main contributors to poor patient outcome. The …

Tumor cells do not exist in isolation in vivo, and carcinogenesis depends on the surrounding
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …

Simple Summary Cancer-associated fibroblasts (CAFs) are key players in the tumor
microenvironment. They are responsible for potentiating growth and metastasis through …

Cancer-associated fibroblasts (CAFs) are a key component of the tumour microenvironment
with diverse functions, including matrix deposition and remodelling, extensive reciprocal …

Simple Summary As our knowledge of cancer as a complex organ comprising tumor cells as
well as surrounding cells within the microenvironment continues to grow, it is imperative to …