New biomarkers of tuberculosis (TB) risk and disease are critical for the urgently needed
control of the ongoing TB pandemic. In a prospective multisite study across Subsaharan …

Background The successful treatment of tuberculosis (TB) requires long-term multidrug
chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are …

The decision to treat active tuberculosis (TB) is dependent on microbiological tests for the
organism or evidence of disease compatible with TB in people with a high demographic risk …

Although tuberculosis (TB) causes more deaths than any other pathogen, most infected
individuals harbor the pathogen without signs of disease. We explored the metabolome of> …

There remains a pressing need for biomarkers that can predict who will progress to active
tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By …

Background A rapid, blood-based triage test that allows targeted investigation for
tuberculosis at the point of care could shorten the time to tuberculosis treatment and reduce …

Background A nonsputum blood test capable of predicting progression of healthy individuals
to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment …

We aimed to characterize metabolites during tuberculosis (TB) disease and identify new
pathophysiologic pathways involved in infection as well as biomarkers of TB onset …

Tuberculosis (TB) and type 2 diabetes mellitus (DM), a major TB risk factor, are both
accompanied by marked alterations in metabolic processes. Dissecting the specific …

Although tuberculosis (TB) is a severe health problem worldwide, the current diagnostic
methods are far from optimal. Metabolomics is increasingly being used in the study of …