Adipocytes as regulators of energy balance and glucose homeostasis
ED Rosen, BM Spiegelman - Nature, 2006 - nature.com
Adipocytes have been studied with increasing intensity as a result of the emergence of
obesity as a serious public health problem and the realization that adipose tissue serves as …
obesity as a serious public health problem and the realization that adipose tissue serves as …
Dynamics of fat cell turnover in humans
Obesity is increasing in an epidemic manner in most countries and constitutes a public
health problem by enhancing the risk for cardiovascular disease and metabolic disorders …
health problem by enhancing the risk for cardiovascular disease and metabolic disorders …
The different shades of fat
V Peirce, S Carobbio, A Vidal-Puig - Nature, 2014 - nature.com
Our understanding of adipose tissue biology has progressed rapidly since the turn of the
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …
Obesity: the two faces of fat.
K Powell - Nature, 2007 - search.ebscohost.com
The article discusses the characteristic of fat cells and its role on obesity and diabetes. It was
noted that fat cells are capable to stop making health molecules such as adiponectin. An …
noted that fat cells are capable to stop making health molecules such as adiponectin. An …
A single-cell atlas of human and mouse white adipose tissue
MP Emont, C Jacobs, AL Essene, D Pant, D Tenen… - Nature, 2022 - nature.com
White adipose tissue, once regarded as morphologically and functionally bland, is now
recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of …
recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of …
A stromal cell population that inhibits adipogenesis in mammalian fat depots
Adipocyte development and differentiation have an important role in the aetiology of obesity
and its co-morbidities,. Although multiple studies have investigated the adipogenic stem and …
and its co-morbidities,. Although multiple studies have investigated the adipogenic stem and …
What we talk about when we talk about fat
ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …
Dynamics of human adipose lipid turnover in health and metabolic disease
Adipose tissue mass is determined by the storage and removal of triglycerides in adipocytes.
Little is known, however, about adipose lipid turnover in humans in health and pathology. To …
Little is known, however, about adipose lipid turnover in humans in health and pathology. To …
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
White adipose tissue displays high plasticity. We developed a system for the inducible,
permanent labeling of mature adipocytes that we called the AdipoChaser mouse. We …
permanent labeling of mature adipocytes that we called the AdipoChaser mouse. We …
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
M Okada-Iwabu, T Yamauchi, M Iwabu, T Honma… - Nature, 2013 - nature.com
Adiponectin secreted from adipocytes binds to adiponectin receptors AdipoR1 and AdipoR2,
and exerts antidiabetic effects via activation of AMPK and PPAR-α pathways, respectively …
and exerts antidiabetic effects via activation of AMPK and PPAR-α pathways, respectively …