[HTML][HTML] Antimicrobial susceptibility testing in biofilm-growing bacteria

MD Macia, E Rojo-Molinero, A Oliver - Clinical Microbiology and Infection, 2014 - Elsevier
Biofilms are organized bacterial communities embedded in an extracellular polymeric matrix
attached to living or abiotic surfaces. The development of biofilms is currently recognized as …

Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?

T Coenye, D Goeres… - Clinical …, 2018 - clinicalmicrobiologyandinfection …
Biofilms are communities of microbial cells that are attached to each other and/or a surface,
and are embedded in an extracellular matrix produced by the bacteria and/or derived from …

Effect of antibiotics on biofilm inhibition and induction measured by real‐time cell analysis

MD Ferrer, JC Rodriguez, L Álvarez… - Journal of applied …, 2017 - academic.oup.com
Aims The purpose of the current work was to study the pattern and dynamics of biofilm
formation in clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis in …

MBEC versus MBIC: the lack of differentiation between biofilm reducing and inhibitory effects as a current problem in biofilm methodology

L Thieme, A Hartung, K Tramm… - Biological procedures …, 2019 - Springer
Background Biofilms are communities of aggregated, matrix-embedded microbial cells
showing a high tolerance to an in principle adequate antibiotic therapy, often resulting in …

Sub-optimal treatment of bacterial biofilms

T Song, M Duperthuy, SN Wai - Antibiotics, 2016 - mdpi.com
Bacterial biofilm is an emerging clinical problem recognized in the treatment of infectious
diseases within the last two decades. The appearance of microbial biofilm in clinical settings …

[25] The MBEC assay system: Multiple equivalent biofilms for antibiotic and biocide susceptibility testing

H Ceri, M Olson, D Morck, D Storey, R Read… - Methods in …, 2001 - Elsevier
Publisher Summary A number of technologies have been developed to study biofilm growth.
Although these technologies produce reproducible biofilms for the study of biofilm growth …

Biofilm antimicrobial susceptibility testing: where are we and where could we be going?

T Coenye - Clinical microbiology reviews, 2023 - Am Soc Microbiol
Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Control of biofilm formation: antibiotics and beyond

A Algburi, N Comito, D Kashtanov… - Applied and …, 2017 - Am Soc Microbiol
Biofilm-associated bacteria are less sensitive to antibiotics than free-living (planktonic) cells.
Furthermore, with variations in the concentration of antibiotics throughout a biofilm, microbial …

Biofilms: an extra hurdle for effective antimicrobial therapy

P Cos, K Tote, T Horemans… - Current pharmaceutical …, 2010 - ingentaconnect.com
Since the 1960's much research has focused on biofilms, ie microbial-derived populations
irreversibly attached to a surface and embedded in a self-produced polymeric matrix. In this …

The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms

H Ceri, ME Olson, C Stremick, RR Read… - Journal of clinical …, 1999 - Am Soc Microbiol
Determination of the MIC, based on the activities of antibiotics against planktonic bacteria, is
the standard assay for antibiotic susceptibility testing. Adherent bacterial populations …