Pulmonary arterial hypertension: the burden of disease and impact on quality of life

M Delcroix, L Howard - European Respiratory Review, 2015 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a debilitating disease that pervades all aspects of
a patient's daily life. It is also increasingly acknowledged that the burden of PAH extends to …

Health-related quality of life and patient-reported outcomes in pulmonary arterial hypertension

H Chen, DB Taichman, RL Doyle - Proceedings of the American …, 2008 - atsjournals.org
Advances in our understanding of the basic pathophysiology of pulmonary arterial
hypertension (PAH) has led to an expanding number of therapeutic options. The ultimate …

[HTML][HTML] Evaluation of disease-specific health-related quality of life in patients with pulmonary arterial hypertension

M Zlupko, MO Harhay, R Gallop, J Shin… - Respiratory …, 2008 - Elsevier
BACKGROUND: Pulmonary arterial hypertension (PAH) remains a debilitating and life-
threatening disease despite improvements in hemodynamics, exercise capacity and survival …

[PDF][PDF] Quality of life of patients with pulmonary arterial hypertension: a meta-analysis

K Sarzyńska, N Świątoniowska-Lonc… - Eur Rev Med …, 2021 - researchgate.net
OBJECTIVE: Pulmonary arterial hypertension (PAH) is a rare condition, with an incidence of
15-50 cases per million annually. Available studies demonstrate that despite the longer …

Understanding the impact of pulmonary arterial hypertension on patients' and carers' lives

L Guillevin, I Armstrong, R Aldrighetti… - European …, 2013 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a rare, debilitating and rapidly progressive
disease. Although there have been important medical advances in PAH management, the …

Quality of life as a prognostic marker in pulmonary arterial hypertension

CJCS Fernandes, BCS Martins, CVP Jardim… - Health and quality of life …, 2014 - Springer
Background Improvement in quality of life together with better survival are the ultimate goals
in the treatment of pulmonary arterial hypertension (PAH) patients. The objective of this …

EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial …

RA Lewis, I Armstrong, C Bergbaum… - European …, 2021 - Eur Respiratory Soc
Health-related quality of life (HRQoL) scores assess symptom burden in pulmonary arterial
hypertension (PAH) but data regarding their role in prognostication and risk stratification are …

Health-related quality of life in patients with pulmonary arterial hypertension

S Shafazand, MK Goldstein, RL Doyle, MA Hlatky… - Chest, 2004 - Elsevier
Study objectives: Patients with pulmonary arterial hypertension (PAH) often present with
dyspnea and severe functional limitations, but their health-related quality of life (HRQOL) …

Evaluating health-related quality of life, work ability, and disability in pulmonary arterial hypertension: an unmet need

M Rubenfire, G Lippo, BD Bodini, F Blasi, L Allegra… - Chest, 2009 - Elsevier
To our knowledge, there are no specific and validated measures of quality of life (QoL) or
degree of disability for pulmonary arterial hypertension (PAH). A review of the literature …

Development of the Pulmonary Arterial Hypertension-Symptoms and Impact (PAH-SYMPACT®) questionnaire: a new patient-reported outcome instrument for PAH

D McCollister, S Shaffer, DB Badesch, A Filusch… - Respiratory …, 2016 - Springer
Background Regulators and clinical experts increasingly recognize the importance of
incorporating patient-reported outcomes (PROs) in clinical studies of therapies for …