[HTML][HTML] Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles

E Bajak, M Fabbri, J Ponti, S Gioria, I Ojea-Jiménez… - Toxicology letters, 2015 - Elsevier
Higher efficacy and safety of nano gold therapeutics require examination of cellular
responses to gold nanoparticles (AuNPs). In this work we compared cellular uptake …

[HTML][HTML] A proteomic approach to investigate AuNPs effects in Balb/3T3 cells

S Gioria, H Chassaigne, D Carpi, A Parracino… - Toxicology letters, 2014 - Elsevier
Although gold nanoparticles (AuNPs) are currently used in several industrial products and
biomedical applications, information about their biological effects is very limited. Thus, it is …

Molecular effects of uptake of gold nanoparticles in HeLa cells

JA Khan, B Pillai, TK Das, Y Singh, S Maiti - ChemBioChem, 2007 - repository.ias.ac.in
Mellow gold: Toxicogenomics of nanoparticles can expose subtle yet clinically relevant
alterations in the intracellular environment that arise from downstream effects of nanoparticle …

The effect of particle size on the genotoxicity of gold nanoparticles

Q Xia, H Li, Y Liu, S Zhang, Q Feng… - Journal of Biomedical …, 2017 - Wiley Online Library
Despite the increasing biomedical applications of gold nanoparticles (AuNPs), their
toxicological effects need to be thoroughly understood. In the present study, the genotoxic …

Toxicity of nano-and ionic silver to embryonic stem cells: a comparative toxicogenomic study

X Gao, VD Topping, Z Keltner, RL Sprando… - Journal of …, 2017 - Springer
Background The widespread application of silver nanoparticles (AgNPs) and silver-
containing products has raised public safety concerns about their adverse effects on human …

Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells

PV AshaRani, S Sethu, HK Lim, G Balaji… - Genome integrity, 2012 - Springer
Background Investigating the cellular and molecular signatures in eukaryotic cells following
exposure to nanoparticles will further our understanding on the mechanisms mediating …

The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome

MI Sierra, A Valdés, AF Fernández… - International journal …, 2016 - Taylor & Francis
Human exposure to nanomaterials and nanoparticles is increasing rapidly, but their effects
on human health are still largely unknown. Epigenetic modifications are attracting ever more …

Cytotoxicity and transcriptomic analysis of silver nanoparticles in mouse embryonic fibroblast cells

S Gurunathan, M Qasim, C Park, H Yoo… - International journal of …, 2018 - mdpi.com
The rapid development of nanotechnology has led to the use of silver nanoparticles (AgNPs)
in biomedical applications, including antibacterial, antiviral, anti-inflammatory, and …

A focus on the genotoxicity of gold nanoparticles

Y Wang, H Zhang, L Shi, J Xu, G Duan, H Yang - Nanomedicine, 2020 - Taylor & Francis
With the development of nanotechnology, nanoparticles (NPs), which are often defined as
particles with at least one dimension ranging between 1 and 100 nm, have been widely …

Surface functionalities of gold nanoparticles impact embryonic gene expression responses

L Truong, SC Tilton, T Zaikova, E Richman… - …, 2013 - Taylor & Francis
Incorporation of gold nanoparticles (AuNPs) into consumer products is increasing; however,
there is a gap in available toxicological data to determine the safety of AuNPs. In this study …