[HTML][HTML] Advances in novel therapeutic approaches for periodontal diseases

MM Haque, K Yerex, A Kelekis-Cholakis, K Duan - BMC Oral Health, 2022 - Springer
Periodontal diseases are pathological processes resulting from infections and inflammation
affecting the periodontium or the tissue surrounding and supporting the teeth. Pathogenic …

[HTML][HTML] Selective antimicrobial therapies for periodontitis: Win the “battle and the war”

M Elashiry, AC Morandini… - International journal of …, 2021 - mdpi.com
Traditional antimicrobial therapies for periodontitis (PD) have long focused on non-selective
and direct approaches. Professional cleaning of the subgingival biofilm by instrumentation of …

Probiotics for periodontal health—Current molecular findings

T Nguyen, H Brody, A Radaic, Y Kapila - Periodontology 2000, 2021 - Wiley Online Library
Dysbiosis of the oral microbiome is associated with a variety of oral and systemic diseases,
including periodontal disease. Oral dysbiosis in periodontal disease leads to an …

Biological approaches to the development of novel periodontal therapies–consensus of the Seventh European Workshop on Periodontology

MS Tonetti, ILC Chapple… - Journal of clinical …, 2011 - Wiley Online Library
Background: Periodontitis remains a major public health issue and current management
approaches have failed to impact upon the most high‐risk proportion of the population and …

[HTML][HTML] Recent advances of therapeutic targets for the treatment of periodontal disease

WJ Kim, Y Soh, SM Heo - Biomolecules & Therapeutics, 2021 - ncbi.nlm.nih.gov
Periodontal disease is primarily associated with bacterial infection such as dental plaque.
Dental plaque, an oral biofilm harboring a complex microbial community, can cause various …

Biofilms

S Eick - Oral Biofilms, 2021 - karger.com
In reality, most microorganisms are not free floating. They exist in biofilms, a community of
many of them from the same species or from other genera and attached to surfaces …

The increasing importance of the oral microbiome in periodontal health and disease

R Siddiqui, Z Badran, A Boghossian, AM Alharbi… - Future Science …, 2023 - Taylor & Francis
Herein, the aim is to discuss the current knowledge of microbiome and periodontal diseases.
Current treatment strategies include mechanical therapy such as root planing, scaling, deep …

[HTML][HTML] Therapeutic and metagenomic potential of the biomolecular therapies against periodontitis and the oral microbiome: current evidence and future perspectives

S Santonocito, S Ferlito, A Polizzi, V Ronsivalle… - International Journal of …, 2022 - mdpi.com
The principles of periodontal therapy are based on the control of microbial pathogens and
host factors that contribute to biofilm dysbiosis, with the aim of modulating the progression of …

Targeted antimicrobial therapy in the microbiome era

VN Stone, P Xu - Molecular oral microbiology, 2017 - Wiley Online Library
Even though the oral microbiome is one of the most complex sites on the body it is an
excellent model for narrow‐spectrum antimicrobial therapy. Current research indicates that …

[HTML][HTML] Probiotic species in the management of periodontal diseases: an overview

Y Zhang, Y Ding, Q Guo - Frontiers in cellular and infection …, 2022 - frontiersin.org
Periodontal diseases are one of the most common chronic inflammatory diseases of the oral
cavity, which are initiated and sustained by pathogenic plaque biofilms. Central to modern …