Three-dimensional hierarchical plasmonic nano-architecture based label-free surface-enhanced Raman spectroscopy detection of urinary exosomal miRNA for …

WH Kim, JU Lee, MJ Jeon, KH Park, SJ Sim - Biosensors and Bioelectronics, 2022 - Elsevier
The urinary exosomal miRNAs are recently emerging prostate cancer (PC)-associated
biomarkers for the early-stage diagnosis and prognosis due to their non-invasiveness …

Quantitative and specific detection of exosomal miRNAs for accurate diagnosis of breast cancer using a surface‐enhanced Raman scattering sensor based on …

JU Lee, WH Kim, HS Lee, KH Park, SJ Sim - Small, 2019 - Wiley Online Library
MicroRNAs in exosomes (exosomal miRNAs) have attracted increased attention as cancer
biomarkers for early diagnosis and prognosis owing to their stability in body fluids. Since …

A microfluidic surface-enhanced Raman scattering (SERS) sensor for microRNA in extracellular vesicles with nucleic acid-tyramine cascade amplification

Y Zhao, X Fang, M Bai, J Zhang, H Yu, F Chen… - Chinese Chemical …, 2022 - Elsevier
Exosomal microRNA (miRNA) is an ideal candidate of noninvasive biomarker for the early
diagnosis of cancer. Sensitive and accurate sensing of abnormal exosomal miRNA plays …

Highly sensitive and reliable detection of microRNA for clinically disease surveillance using SERS biosensor integrated with catalytic hairpin assembly amplification …

S Weng, D Lin, S Lai, H Tao, T Chen, M Peng… - Biosensors and …, 2022 - Elsevier
MicroRNAs (miRNAs) play an important regulatory role in several diseases, especially as a
class of promising biomarkers for cancer diagnosis and prognosis. Here, a biosensor based …

Nanoarchitectonics-assisted simultaneous fluorescence detection of urinary dual miRNAs for noninvasive diagnosis of prostate cancer

P Jiang, Y Bai, L Yan, P Feng, K Huang… - Analytical …, 2023 - ACS Publications
Herein, we report a fluorescence strategy for the homogeneous and simultaneous analysis
of urine miRNA-375 and miRNA-148a. The target miRNAs in urine bonded the devised …

Quantitative detection of exosomal microRNA extracted from human blood based on surface-enhanced Raman scattering

D Ma, C Huang, J Zheng, J Tang, J Li, J Yang… - Biosensors and …, 2018 - Elsevier
Since the nature of the exosomal lipid bilayer can allow miRNAs to be protected from
degradation by cellular RNAses in body fluids, exosomal microRNA (miRNA) has become …

Simultaneous surface-enhanced Raman spectroscopy detection of multiplexed microRNA biomarkers

W Zhou, YF Tian, BC Yin, BC Ye - Analytical chemistry, 2017 - ACS Publications
Simultaneous detection of cancer biomarkers holds great promise for the early diagnosis of
cancer. In the present work, an ultrasensitive and reliable surface-enhanced Raman …

Well-ordered Au nanoarray for sensitive and reproducible detection of hepatocellular carcinoma-associated miRNA via CHA-assisted SERS/fluorescence dual-mode …

X Huang, H Tian, L Huang, Q Chen, Y Yang… - Analytical …, 2023 - ACS Publications
Ultra-sensitive detection of cancer-related biomarkers in serum is of great significance for
early diagnosis, treatment, prognosis, and staging of cancer. In this work, we proposed a …

Simultaneous dual-targeted monitoring of breast cancer circulating miRNA via surface-enhanced Raman spectroscopy

J Kim, J Park, J Ki, HW Rho, YM Huh, E Kim… - Biosensors and …, 2022 - Elsevier
Breast cancer is one of the most common cancers globally. Because the 5-year survival rate
of breast cancer greatly increases when treated in its initial stage, the importance of early …

Ultrasensitive simultaneous detection of multiplex disease-related nucleic acids using double-enhanced surface-enhanced Raman scattering nanosensors

R Guo, F Yin, Y Sun, L Mi, L Shi, Z Tian… - ACS applied materials & …, 2018 - ACS Publications
Developing ultrasensitive probes holds great significance for simultaneous detection of
multiplexed cancer-associated nucleic acids. Bimetallic nanoparticles containing silver may …