A microRNA screen identifies the Wnt signaling pathway as a regulator of the interferon response during flavivirus infection

JL Smith, S Jeng, SK McWeeney, AJ Hirsch - Journal of virology, 2017 - Am Soc Microbiol
The impact of mosquito-borne flavivirus infections worldwide is significant, and many critical
aspects of these viruses' biology, including virus-host interactions, host cell requirements for …

Regulatory role of host microRNAs in flaviviruses infection

W Cai, Y Pan, A Cheng, M Wang, Z Yin… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNA that affect mRNA abundance or translation
efficiency by binding to the 3′ UTR of the mRNA of the target gene, thereby participating in …

MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-λ1

Y Li, J Xie, X Xu, J Wang, F Ao, Y Wan, Y Zhu - Protein & cell, 2013 - Springer
Interferon (IFN)-mediated pathways are a crucial part of the cellular response against viral
infection. Type III IFNs, which include IFN-λ1, 2 and 3, mediate antiviral responses similar to …

A glance at subgenomic flavivirus RNAs and microRNAs in flavivirus infections

L Bavia, ALP Mosimann, MN Aoki… - Virology journal, 2016 - Springer
The family Flaviviridae comprises a wide variety of viruses that are distributed worldwide,
some of which are associated with high rates of morbidity and mortality. There are neither …

Expression of mosquito microRNA Aae-miR-2940-5p is downregulated in response to West Nile virus infection to restrict viral replication

A Slonchak, M Hussain, S Torres, S Asgari… - Journal of …, 2014 - Am Soc Microbiol
West Nile virus (WNV) is an enveloped virus with a single-stranded positive-sense RNA
genome from the Flaviviridae family. WNV is spread by mosquitoes and able to infect …

Human microRNA miR-532-5p exhibits antiviral activity against West Nile virus via suppression of host genes SESTD1 and TAB3 required for virus replication

A Slonchak, RP Shannon, G Pali… - Journal of virology, 2016 - Am Soc Microbiol
West Nile virus (WNV) is a mosquito-transmitted flavivirus that naturally circulates between
mosquitos and birds but can also infect humans, causing severe neurological disease. The …

Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

RL Skalsky, DL Vanlandingham, F Scholle, S Higgs… - BMC genomics, 2010 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally
regulate gene expression in a variety of organisms, including insects, vertebrates, and …

MicroRNA-30a Modulates Type I Interferon Responses to Facilitate Coxsackievirus B3 Replication Via Targeting Tripartite Motif Protein 25

J Li, Y Xie, L Li, X Li, L Shen, J Gong… - Frontiers in …, 2021 - frontiersin.org
Viral myocarditis is caused by a viral infection and characterized by the inflammation of the
myocardium. Coxsackievirus B3 (CVB3) infection is one of the most common among the …

miR-21 promotes dengue virus serotype 2 replication in HepG2 cells

S Kanokudom, T Vilaivan, N Wikan, C Thepparit… - Antiviral Research, 2017 - Elsevier
Infection with the mosquito transmitted dengue virus (DENV) remains a significant worldwide
public health problem. While the majority of infections are asymptomatic, infection can result …

Noncoding subgenomic flavivirus RNA is processed by the mosquito RNA interference machinery and determines West Nile virus transmission by Culex pipiens …

GP Göertz, JJ Fros, P Miesen, CBF Vogels… - Journal of …, 2016 - Am Soc Microbiol
Flaviviruses, such as Zika virus, yellow fever virus, dengue virus, and West Nile virus (WNV),
are a serious concern for human health. Flaviviruses produce an abundant noncoding …