The brain-derived neurotrophic factor: missing link between sleep deprivation, insomnia, and depression

M Rahmani, F Rahmani, N Rezaei - Neurochemical research, 2020 - Springer
The brain-derived neurotrophic factor (BDNF) mediates the plasticity-related changes that
associate with memory processing during sleep. Sleep deprivation and chronic stress are …

BDNF in sleep, insomnia, and sleep deprivation

K Schmitt, E Holsboer-Trachsler, A Eckert - Annals of medicine, 2016 - Taylor & Francis
The protein brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family
of growth factors involved in plasticity of neurons in several brain regions. There are …

[HTML][HTML] Fast BDNF serum level increase and diurnal BDNF oscillations are associated with therapeutic response after partial sleep deprivation

M Giese, J Beck, S Brand, F Muheim… - Journal of psychiatric …, 2014 - Elsevier
Objective Preclinical and clinical studies support a role for brain-derived neurotrophic factor
(BDNF) in the pathophysiology of stress-related mood disorders. Furthermore, BDNF seems …

[HTML][HTML] BDNF: an indicator of insomnia?

M Giese, E Unternaehrer, H Hüttig, J Beck… - Molecular …, 2014 - nature.com
In the last decade, brain-derived neurotrophic factor (BDNF) has become increasingly
accepted as a central mediator of the effects of stress on neuronal plasticity and its …

A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep

U Faraguna, VV Vyazovskiy, AB Nelson… - Journal of …, 2008 - Soc Neuroscience
Slow-wave activity (SWA), the EEG power between 0.5 and 4 Hz during non-rapid eye
movement (NREM) sleep, is one of the best characterized markers of sleep need, because it …

[HTML][HTML] Blood brain-derived neurotrophic factor (BDNF) and major depression: do we have a translational perspective?

B Arosio, FR Guerini, RCO Voshaar… - Frontiers in behavioral …, 2021 - frontiersin.org
Major depressive disorder (MDD) affects millions of people worldwide and is a leading
cause of disability. Several theories have been proposed to explain its pathological …

[HTML][HTML] Relationship between brain-derived neurotrofic factor (Bdnf) and sleep on depression: a critical review

BC Monteiro, S Monteiro, M Candida… - Clinical practice and …, 2017 - ncbi.nlm.nih.gov
Abstract The Brain-Derived Neurotrofic Factor (BDNF) is one of the most important
neurotrophins in the brain and it is suggested influences the activity of the serotonergic …

Association of BDNF Val66Met polymorphism and brain BDNF levels with major depression and suicide

MM Youssef, MD Underwood, YY Huang… - International Journal …, 2018 - academic.oup.com
Background Brain-derived neurotrophic factor is implicated in the pathophysiology of major
depressive disorder and suicide. Both are partly caused by early life adversity, which …

[HTML][HTML] Brain-derived neurotrophic factor and major depressive disorder: evidence from meta-analyses

T Kishi, R Yoshimura, T Ikuta, N Iwata - Frontiers in psychiatry, 2018 - frontiersin.org
Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF) is
associated with the pathophysiology of major depressive disorder (MDD). In this mini review …

Peripheral brain-derived neurotrophic factor (BDNF) in insomnia: A systematic review and meta-analysis

A Ballesio, A Zagaria, DG Curti, R Moran… - Sleep medicine …, 2023 - Elsevier
The brain-derived neurotrophic factor (BDNF) is associated with emotional and cognitive
functioning, and it is considered a transdiagnostic biomarker for mental disorders. Literature …