[HTML][HTML] Exosome-based vaccines: history, current state, and clinical trials
P Santos, F Almeida - Frontiers in immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular
communication system in crucial processes such as inflammation, cell proliferation, and …
communication system in crucial processes such as inflammation, cell proliferation, and …
Tumor-derived exosomes: the next generation of promising cell-free vaccines in cancer immunotherapy
M Naseri, M Bozorgmehr, M Zöller… - …, 2020 - Taylor & Francis
Identification of immunogenic tumor antigens that are efficiently processed and delivered by
dendritic cells to prime the immune system and to induce an appropriate immune response …
dendritic cells to prime the immune system and to induce an appropriate immune response …
Prospects for exosomes in immunotherapy of cancer
G Mignot, S Roux, C Thery, E Ségura… - Journal of cellular and …, 2006 - Wiley Online Library
Exosomes are nanometer sized membrane vesicles invaginating from multivesicular bodies
and secreted from epithelial and hematopoietic cells. They were first described “in vitro” but …
and secreted from epithelial and hematopoietic cells. They were first described “in vitro” but …
The function and clinical application of extracellular vesicles in innate immune regulation
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
Extracellular vesicles as next generation immunotherapeutics
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
Potential application of exosomes in vaccine development and delivery
MN Huda, M Nurunnabi - Pharmaceutical Research, 2022 - Springer
Exosomes are cell-derived components composed of proteins, lipid, genetic information,
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …
Exosomes as immunotheranostic nanoparticles
G Natasha, B Gundogan, A Tan, Y Farhatnia, W Wu… - Clinical …, 2014 - Elsevier
Background Exosomes are small biological membrane vesicles that measure 30 to 100 nm
in diameter. They are involved in a wide array of biological activities, such as cell-cell …
in diameter. They are involved in a wide array of biological activities, such as cell-cell …
Recent advances in exosome-based immunotherapy applied to cancer
Cancer stands as a prominent contributor to global mortality rates, necessitating immediate
attention toward the exploration of its treatment options. Extracellular vesicles have been …
attention toward the exploration of its treatment options. Extracellular vesicles have been …
Immune cell-derived extracellular vesicles–new strategies in cancer immunotherapy
P Yang, Y Peng, Y Feng, Z Xu, P Feng, J Cao… - Frontiers in …, 2021 - frontiersin.org
Immune cell-derived extracellular vesicles (EVs) have increasingly become the focus of
research due to their unique characteristics and bioinspired applications. They are lipid …
research due to their unique characteristics and bioinspired applications. They are lipid …
[HTML][HTML] Immunotherapy based on dendritic cell-targeted/-derived extracellular vesicles—a novel strategy for enhancement of the anti-tumor immune response
O Markov, A Oshchepkova, N Mironova - Frontiers in pharmacology, 2019 - frontiersin.org
Dendritic cell (DC)-based anti-tumor vaccines have great potential for the treatment of
cancer. To date, a large number of clinical trials involving DC-based vaccines have been …
cancer. To date, a large number of clinical trials involving DC-based vaccines have been …