New aspects of the kidney in the regulation of fibroblast growth factor 23 (FGF23) and mineral homeostasis

ML Mace, K Olgaard, E Lewin - International journal of molecular sciences, 2020 - mdpi.com
The bone-derived hormone fibroblast growth factor 23 (FGF23) acts in concert with
parathyroid hormone (PTH) and the active vitamin D metabolite calcitriol in the regulation of …

The regulation of FGF23 under physiological and pathophysiological conditions

S Rausch, M Föller - Pflügers Archiv-European Journal of Physiology, 2022 - Springer
Abstract Fibroblast growth factor 23 (FGF23) is an important bone hormone that regulates
phosphate homeostasis in the kidney along with active vitamin D (1, 25 (OH) 2D3) and …

Clinical Significance of FGF‐23 in Patients with CKD

D Russo, Y Battaglia - International Journal of Nephrology, 2011 - Wiley Online Library
FGF23 is a bone‐derived hormone that plays an important role in the regulation of
phosphate and 1, 25‐dihydroxy vitamin D metabolism. FGF23 principally acts in the kidney …

The fibroblast growth factor 23: a new player in the field of cardiovascular, bone and renal disease

M Cozzolino, S Mazzaferro - Current Vascular Pharmacology, 2010 - ingentaconnect.com
Recently, a new view into the molecular mechanisms of phosphate homeostasis and
secondary hyperparathyroidism pathogenesis has been proposed, with Fibroblast Growth …

The role of fibroblast growth factor 23 in inflammation and anemia

B Czaya, C Faul - International journal of molecular sciences, 2019 - mdpi.com
In patients with chronic kidney disease (CKD), adverse outcomes such as systemic
inflammation and anemia are contributing pathologies which increase the risks for …

Physiological actions of fibroblast growth factor-23

RG Erben - Frontiers in endocrinology, 2018 - frontiersin.org
Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate
reabsorption and vitamin D hormone synthesis in the kidney. At physiological concentrations …

[PDF][PDF] New insights into the role of fibroblast growth factor 23 in chronic kidney disease

K Nakai, H Komaba, M Fukagawa - J Nephrol, 2010 - researchgate.net
ABSTRACT Fibroblast growth factor 23 (FGF23) is a recently identified bone-derived
hormone that regulates phosphate and 1, 25-dihydroxyvitamin D metabolism. FGF23 …

[HTML][HTML] FGF23–parathyroid interaction: implications in chronic kidney disease

H Komaba, M Fukagawa - Kidney international, 2010 - Elsevier
Over the past few years there have been considerable advances in our understanding of the
physiological regulation of mineral homeostasis. One of the most important breakthroughs is …

Role of fibroblast growth factor 23 in health and in chronic kidney disease

M Fukagawa, T Nii-Kono… - Current opinion in …, 2005 - journals.lww.com
FGF23 is a physiological regulator of phosphate homeostasis. Excessive activity of FGF23
with normal renal function results in hypophosphatemia, low 1, 25-dihydroxyvitamin D …

FGF23 beyond phosphotropic hormone

Y Takashi, S Fukumoto - Trends in Endocrinology & Metabolism, 2018 - cell.com
Fibroblast growth factor (FGF) 23 is a bone-derived phosphotropic hormone that regulates
phosphate and vitamin D metabolism. FGF23 mainly affects kidney function via the FGF …