Kinetics of gene expression may be oscillatory due to the feedbacks between the mRNA,
non-coding RNA and protein synthesis. In complex genetic networks, the kinetic oscillations …

Kinetics of gene expression may be bistable or oscillatory due to the feedbacks between the
RNA and protein synthesis. In complex genetic networks, kinetic oscillations may influence …

Randomness in gene transcription can result in fluctuations (noise) of messenger RNA
(mRNA) levels, leading to phenotypic plasticity in the isogenic populations of cells. Recent …

The linear noise approximation is a useful method for stochastic noise evaluations in genetic
regulatory networks, where the covariance equation described as a Lyapunov equation …

The origin of stochastic fluctuations in gene expression has received considerable attention
recently. Fluctuations in gene expression are particularly pronounced in cellular systems …

The noisy fluctuation of chemical reactions should profoundly affect the oscillatory dynamics
of gene circuit. In this paper a prototypical genetic oscillator, repressilator, is numerically …

Background The linear noise approximation (LNA) is commonly used to predict how noise is
regulated and exploited at the cellular level. These predictions are exact for reaction …

Signal transduction pathways play a major role in many important aspects of cellular
function eg cell division, apoptosis. One important class of signal transduction pathways is …

Computer simulations of large genetic networks are often extremely time consuming
because, in addition to the biologically interesting translation and transcription reactions …

The components that are central to cellular processing are proteins, whose production is
regulated by other proteins known as transcription factors. Proteins are products of genes …