An expansion of the cerebral neocortex is thought to be the foundation for the unique
intellectual abilities of humans. It has been suggested that an increase in the proliferative …

The evolutionary expansion of the mammalian brain, notably the neocortex, provides a
platform for the higher cognitive abilities that characterize humans. Cortical expansion is …

Highlights•Human-specific aspects of cortical expansion.•Genomic changes affecting
cortical neurogenesis.•Human-specific genes affecting cortical progenitors.Neocortex …

An increase in the diversity of neural progenitor subtypes and folding of the cerebral cortex
are characteristic features which appeared during the evolution of the mammalian brain …

Human neocortex expansion likely contributed to the remarkable cognitive abilities of
humans. This expansion is thought to primarily reflect differences in proliferation versus …

Expansion and folding of the cerebral cortex are landmark features of mammalian brain
evolution, which are recapitulated during embryonic development. Neural stem cells and …

The human brain has undergone rapid expansion since humans diverged from other great
apes, but the mechanism of this human-specific enlargement is still unknown. Here, we use …

Transgenic mice expressing a stabilized β-catenin in neural precursors develop enlarged
brains with increased cerebral cortical surface area and folds resembling sulci and gyri of …

The dramatic evolutionary expansion of the cerebral cortex of Homo sapiens underlies our
unique higher cortical functions, and therefore bears on the ultimate issue of what makes us …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …