Dietary flavonoid carvacrol triggers the apoptosis of human breast cancer MCF-7 cells via the p53/Bax/Bcl-2 axis

A Moradipour, H Dariushnejad, C Ahmadizadeh… - Medical Oncology, 2022 - Springer
Recently, numerous studies have shown that natural compounds such as carvacrol can be
used as therapeutic agents for medicinal purposes. Although carvacrol was found to …

Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB 231

KM Arunasree - Phytomedicine, 2010 - Elsevier
PURPOSE: Although the anti-tumor effects of carvacrol have been demonstrated earlier, the
exact underlying molecular mechanisms involved in its action have not been defined and in …

Carvacrol promotes cell cycle arrest and apoptosis through PI3K/AKT signaling pathway in MCF-7 breast cancer cells

A Mari, G Mani, SN Nagabhishek, G Balaraman… - Chinese journal of …, 2021 - Springer
Objective To examine the role of carvacrol in modulating PI3K/AKT signaling involved in
human breast cancer pathogenesis using in vitro experimental model MCF-7 cells. Methods …

Cytotoxicity and pro-apoptotic activity of carvacrol on human breast cancer cell line MCF-7

AA Al-Fatlawi, A Ahmad - World Journal of Pharmaceutical …, 2014 - wjpsonline.com
The aim of this study was to evaluate anticancer activity of carvacrol against human breast
cancer cell line (MCF-7). Cytotoxic of carvacrol was determined by MTT and LDH assays …

Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2

Q Yin, F Yan, XY Zu, Y Wu, X Wu, M Liao, S Deng… - Cytotechnology, 2012 - Springer
Carvacrol is one of the members of monoterpene phenol and is present in the volatile oils of
Thymus vulgaris, Carum copticum, origanum and oregano. It is a safe food additive …

Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells

K Fan, X Li, Y Cao, H Qi, L Li, Q Zhang, H Sun - Anti-cancer drugs, 2015 - journals.lww.com
Colon cancer is one of the most common malignancies worldwide and has a high mortality
rate. Carvacrol is a major component of oregano and thyme essential oils and shows …

Carvacrol exhibits chemopreventive potential against cervical cancer cells via caspase-dependent apoptosis and abrogation of cell cycle progression

A Ahmad, IA Ansari - Anti-Cancer Agents in Medicinal …, 2021 - ingentaconnect.com
Background: The carcinogenesis of the uterine cervix is predominantly initiated with the
consistent infection of the Human Papilloma Virus (HPV). Owing to the side effects of …

Effects of natural phenolic compound carvacrol on the human gastric adenocarcinoma (AGS) cells in vitro

A Günes-Bayir, HS Kiziltan, A Kocyigit, EM Güler… - Anti-cancer …, 2017 - journals.lww.com
Gastric cancer (GC) is the most common cause of morbidity and mortality because of cancer.
Medicinal plants containing polyphenolic compounds have gained importance in anticancer …

Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells

Z Xu, X Chen, S Fu, J Bao, Y Dang… - The American Journal …, 2012 - World Scientific
Dehydrocorydaline is an alkaloid isolated from traditional Chinese herb Corydalis yanhusuo
WT Wang. We discovered that it possessed anti-tumor potential during screening of anti …

A New Flavanone from Chromolaena tacotana (Klatt) RM King and H. Rob, Promotes Apoptosis in Human Breast Cancer Cells by Downregulating Antiapoptotic …

G Mendez-Callejas, R Torrenegra, D Muñoz, C Celis… - Molecules, 2022 - mdpi.com
Chromolaena tacotana is a source of flavonoids with antiproliferative properties in human
breast cancer cells, the most common neoplasm diagnosed in patients worldwide. Until now …