The term congenital neutropenia encompasses a family of neutropenic disorders, both
permanent and intermittent, severe (< 0.5 G/l) or mild (between 0.5-1.5 G/l), which may also …

Congenital neutropenia is characterized by chronic neutropenia caused by a constitutional
genetic defect. Epidemiologic investigations of congenital neutropenia aim to define the …

Current knowledge on the molecular pathogenesis of severe congenital neutropenia
indicates that the clinical diagnosis includes a heterogeneous group of disorders following …

Neutrophils have an important role in host defense and acute inflammation. It is well known
that susceptibility to infection increases when the neutrophil count is low. Neutropenia were …

Neutropenia is a dangerous and potentially fatal condition that renders patients vulnerable
to recurrent infections. Its severity is commensurate with the absolute count of neutrophil …

Severe congenital neutropenia (CN) includes a variety of hematologic disorders
characterized by severe neutropenia, with absolute neutrophil counts (ANC) below 0.5× …

The Many Causes of Severe Congenital Neutropenia | NEJM Skip to main content Access
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Neutropenia, defined as an absolute neutrophil count (ANC)< 1.5× 10 9/L, encompasses a
wide range of diagnoses, from normal variants to life-threatening acquired and congenital …

Neutropenia, usually defined as a blood neutrophil count< 1· 5× 109/l, is a common medical
problem for children and adults. There are many causes for neutropenia, and at each stage …

Congenital neutropenia (CN) comprises a heterogeneous group of genetically determined
disorders characterized by a decrease of neutrophils in the peripheral blood. Low numbers …