A higher dietary ratio of long-chain omega-3 to total omega-6 fatty acids for prevention of COX-2-dependent adenocarcinomas

JJ DiNicolantonio, MF McCarty, S Chatterjee… - Nutrition and …, 2014 - Taylor & Francis
Compelling evidence that daily low-dose aspirin decreases risk for a number of
adenocarcinomas likely reflects the fact that a modest but consistent inhibition of …

Marine-derived omega-3 fatty acids: fishing for clues for cancer prevention

CJ Fabian - 2013 - ascopubs.org
Omega-3 fatty acids (FA) are polyunsaturated essential FA with anti-inflammatory properties.
The most potent are the marine-derived eicosapentaenoic acid (EPA) and docosahexaenoic …

Omega-3 fatty acids as cancer chemopreventive agents

DP Rose, JM Connolly - Pharmacology & therapeutics, 1999 - Elsevier
There is both epidemiologic and experimental evidence that the long-chain omega-3 fatty
acids (FAs), which occur at high levels in some fish oils, exert protective effects against some …

Dietary fatty acids, COX-2 blockade, and carcinogenesis

RA Karmali - COX-2 blockade in cancer prevention and therapy, 2003 - Springer
Dietary fatty acids have been shown to exert a wide variety of actions in carcinogenesis in
experimental models, and they are implicated in the development of several human cancers …

Customized prevention trials could resolve the controversy of the effects of omega-3 fatty acids on cancer

K El-Bayoumy, A Manni - Nutrition and cancer, 2020 - Taylor & Francis
Literature data revealed that the benefits of consuming omega-3 fatty acid (n-3FA)
supplements such as fish oil with the goal of reducing the incidence of chronic diseases …

Effects of omega-3 fatty acids on cancer risk: a systematic review

CH MacLean, SJ Newberry, WA Mojica, P Khanna… - Jama, 2006 - jamanetwork.com
ContextOmega-3 fatty acids are purported to reduce the risk of cancer. Studies have
reported mixed results. ObjectiveTo synthesize published and unpublished evidence to …

Chemopreventive effects of omega-3 fatty acids

JR Lupton, RS Chapkin - Cancer Chemoprevention: Promising Cancer …, 2004 - Springer
Evidence increasingly suggests that 1 ω-3 fatty acids, particularly eicosapentaenoic acid
(20: 5n-3)(EPA) and docosahexaenoic acid (22: 6n-3)(DHA) are protective against cancer …

Metabolism of exogenous and endogenous arachidonic acid in cancer

SD Phinney - Dietary Fats, Lipids, Hormones, and Tumorigenesis …, 1996 - Springer
Epidemiologic evidence in humans and controlled trials in animal models indicate that total
dietary fat increases the risk of cancer. The animal evidence indicates that the greatest …

Dietary Epa Reduces Tumor Load in ApcMin/+ Mice by Altering Arachidonic Acid Metabolism, But Conjugated Linoleic Acid, Gamma- And Alpha-Linolenic Acids …

J Whelan, MB Hansen Petrik, MF McEntee… - Eicosanoids and Other …, 2002 - Springer
Colorectal cancer is the second leading cause of cancer deaths in the United States and
several lines of evidence implicate environmental factors, specifically dietary components …

[HTML][HTML] Consumption of fish and ω-3 fatty acids and cancer risk: an umbrella review of meta-analyses of observational studies

KH Lee, HJ Seong, G Kim, GH Jeong, JY Kim… - Advances in …, 2020 - Elsevier
Multiple studies have suggested that ω-3 fatty acid intake may have a protective effect on
cancer risk; however, its true association with cancer risk remains controversial. We …