Papain-like protease is an essential enzyme in the proteolytic processing required for the
replication of SARS-CoV-2. Accordingly, such an enzyme is an important target for the …

Abstract SARS-CoV-2 papain-like protease is considered as an important potential target for
anti-SARS-CoV-2 drug discovery due to its crucial roles in viral spread and innate immunity …

SARS-CoV-2 is a new strain of Coronavirus that caused the pneumonia outbreak in Wuhan,
China and has spread to over 200 countries of the world. It has received worldwide attention …

The emergent outbreak caused by severe acute respiratory syndrome coronavirus 2
continues spreading and causing huge social and economic disruption. Papain-like …

As an extension of our research against COVID-19, a multiphase in silico approach was
applied in the selection of the three most common inhibitors (Glycyrrhizoflavone (76) …

COVID-19 and its causative organism SARS-CoV2 that emerged from Wuhan city, China
have paralyzed the world. With no clinically approved drugs, the global health system is …

The coronavirus disease infections (COVID-19) caused by a new type of coronavirus (SARS-
CoV-2) have been emerging in the entire world. Therefore, it is necessary to find out …

In continuation of our antecedent work against COVID-19, three natural compounds, namely,
Luteoside C (130), Kahalalide E (184), and Streptovaricin B (278) were determined as the …

Due to the unavailability specific drugs or vaccines (FDA approved) that can cure COVID-19,
the development of potent antiviral drug candidates/therapeutic molecules against COVID …

The papain-like protease (PL pro) is vital for the replication of coronaviruses (CoVs), as well
as for escaping innate-immune responses of the host. Hence, it has emerged as an …