[HTML][HTML] Mouse lipidomics reveals inherent flexibility of a mammalian lipidome

MA Surma, MJ Gerl, R Herzog, J Helppi, K Simons… - Scientific reports, 2021 - nature.com
Lipidomics has become an indispensable method for the quantitative assessment of lipid
metabolism in basic, clinical, and pharmaceutical research. It allows for the generation of …

Lipidomics as a principal tool for advancing biomedical research

SM Lam, G Shui - Journal of Genetics and Genomics, 2013 - Elsevier
Lipidomics, which targets at the construction of a comprehensive map of lipidome
comprising the entire lipid pool within a cell or tissue, is currently emerging as an …

Lipidomics applications for disease biomarker discovery in mammal models

YY Zhao, XL Cheng, RC Lin, F Wei - Biomarkers in medicine, 2015 - Taylor & Francis
Lipidomics is a lipid-targeted metabolomics approach focusing on comprehensive analysis
of all lipids with which they interact in biology systems. Recent technological advances in …

[HTML][HTML] BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS

C Gaud, BC Sousa, A Nguyen, M Fedorova, Z Ni… - …, 2021 - ncbi.nlm.nih.gov
Lipidomics increasingly describes the quantification using mass spectrometry of all lipids
present in a biological sample. As the power of lipidomics protocols increase, thousands of …

[HTML][HTML] The foundations and development of lipidomics

X Han, RW Gross - Journal of lipid research, 2022 - ASBMB
For over a century, the importance of lipid metabolism in biology was recognized but difficult
to mechanistically understand due to the lack of sensitive and robust technologies for …

Lipidomics: coming to grips with lipid diversity

A Shevchenko, K Simons - Nature reviews Molecular cell biology, 2010 - nature.com
Although lipids are biomolecules with seemingly simple chemical structures, the molecular
composition of the cellular lipidome is complex and, currently, poorly understood. The exact …

High-coverage lipidomics for functional lipid and pathway analyses

SM Lam, Z Wang, B Li, G Shui - Analytica Chimica Acta, 2021 - Elsevier
Rapid advances in front-end separation approaches and analytical technologies have
accelerated the development of lipidomics, particularly in terms of increasing analytical …

[HTML][HTML] Recent advances in expanding the coverage of the lipidome

S Tumanov, JJ Kamphorst - Current opinion in biotechnology, 2017 - Elsevier
Highlights•The extreme diversity of the lipidome poses a significant analytical challenge.•A
variety of mass spectrometry-based approaches exist for the analysis of lipids.•Combining …

[PDF][PDF] Lipidomics: a global approach to lipid analysis in biological systems

AD Watson - Journal of lipid research, 2006 - Citeseer
Lipids are water-insoluble molecules that have a wide variety of functions within cells,
including: 1) maintenance of electrochemical gradients; 2) subcellular partitioning; 3) first …

[HTML][HTML] Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis

L Yetukuri, M Katajamaa, G Medina-Gomez… - BMC systems …, 2007 - Springer
Background Lipids are an important and highly diverse class of molecules having structural,
energy storage and signaling roles. Modern analytical technologies afford screening of …