How UV light touches the brain and endocrine system through skin, and why

AT Slominski, MA Zmijewski, PM Plonka… - …, 2018 - academic.oup.com
The skin, a self-regulating protective barrier organ, is empowered with sensory and
computing capabilities to counteract the environmental stressors to maintain and restore …

Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system

RM Slominski, JY Chen, C Raman… - Proceedings of the …, 2024 - National Acad Sciences
Ultraviolet radiation (UVR) is primarily recognized for its detrimental effects such as
cancerogenesis, skin aging, eye damage, and autoimmune disorders. With exception of …

[HTML][HTML] UVB activates hypothalamic–pituitary–adrenal axis in C57BL/6 mice

C Skobowiat, AT Slominski - Journal of Investigative Dermatology, 2015 - Elsevier
To test the hypothesis that UVB can activate the hypothalamic–pituitary–adrenal (HPA) axis,
the shaved back skin of C57BL/6 mice was exposed to 400 mJ cm− 2 of UVB or was sham …

[HTML][HTML] Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior

R Parikh, E Sorek, S Parikh, K Michael, L Bikovski… - Cell Reports, 2021 - cell.com
Ultraviolet (UV) light affects endocrinological and behavioral aspects of sexuality via an
unknown mechanism. Here we discover that ultraviolet B (UVB) exposure enhances the …

Ultraviolet radiation on the skin: a painful experience?

DM Lopes, SB McMahon - CNS neuroscience & therapeutics, 2016 - Wiley Online Library
Excessive exposure of skin to ultraviolet radiation (UVR) has dramatic clinical effects in
humans, and it is a significant public health concern. Discomfort and sensory changes …

Exposure to ultraviolet radiation in the modulation of human diseases

PH Hart, M Norval, SN Byrne… - Annual Review of …, 2019 - annualreviews.org
This review focuses primarily on the beneficial effects for human health of exposure to
ultraviolet radiation (UVR). UVR stimulates anti-inflammatory and immunosuppressive …

UV-light-induced signal cascades and skin aging

L Rittié, GJ Fisher - Ageing research reviews, 2002 - Elsevier
UV irradiation acts as a broad activator of cell surface growth factor and cytokine receptors.
This ligand-independent receptor activation induces multiple downstream signaling …

Anatomy and Function of the Skin

Y Gilaberte, L Prieto-Torres, I Pastushenko… - Nanoscience in …, 2016 - Elsevier
The skin is the largest human organ. It has three layers: the epidermis, the dermis, and the
hypodermis. The epidermis is the outer layer, formed by a stratified, squamous epithelium …

Skin exposure to ultraviolet B rapidly activates systemic neuroendocrine and immunosuppressive responses

C Skobowiat, AE Postlethwaite… - Photochemistry and …, 2017 - Wiley Online Library
The back skin of C57 BL/6 mice was exposed to a single 400 mJ cm− 2 dose of ultraviolet B
(UVB), and parameters of hypothalamic–pituitary–adrenal (HPA) axis in relation to immune …

Animals under the sun: effects of ultraviolet radiation on mammalian skin

A Slominski, J Pawelek - Clinics in dermatology, 1998 - cidjournal.com
Life on earth since inception has depended on a constant source of energy from the burning
gasses of our sun. This electromagnetic energy has both life-giving and life-endangering …