Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
[HTML][HTML] Imaging the Nigrosome 1 in the substantia nigra using susceptibility weighted imaging and quantitative susceptibility mapping: An application to Parkinson's …
Parkinson's disease (PD) is a clinically heterogeneous chronic progressive neuro-
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …
Nigrosome imaging and neuromelanin sensitive MRI in diagnostic evaluation of parkinsonism
Background Recent developments in magnetic resonance imaging (MRI) techniques have
offered new research opportunities to visualize in vivo substantia nigra pathology in …
offered new research opportunities to visualize in vivo substantia nigra pathology in …
Comparative study of MRI biomarkers in the substantia nigra to discriminate idiopathic Parkinson disease
N Pyatigorskaya, B Magnin, M Mongin… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Several new MR imaging techniques have shown
promising results in patients with Parkinson disease; however, the comparative diagnostic …
promising results in patients with Parkinson disease; however, the comparative diagnostic …
[HTML][HTML] Imaging iron and neuromelanin simultaneously using a single 3D gradient echo magnetization transfer sequence: Combining neuromelanin, iron and the …
Diagnosing early stage Parkinson's disease (PD) is still a clinical challenge. Previous
studies using iron, neuromelanin (NM) or the Nigrosome-1 (N1) sign in the substantia nigra …
studies using iron, neuromelanin (NM) or the Nigrosome-1 (N1) sign in the substantia nigra …
Visualization of nigrosome 1 and its loss in PD: pathoanatomical correlation and in vivo 7 T MRI
Objective: This study assessed whether high-resolution 7 T MRI allowed direct in vivo
visualization of nigrosomes, substructures of the substantia nigra pars compacta (SNpc) …
visualization of nigrosomes, substructures of the substantia nigra pars compacta (SNpc) …
Loss of substantia nigra hyperintensity on 7 Tesla MRI of Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy
JM Kim, HJ Jeong, YJ Bae, SY Park, E Kim… - Parkinsonism & related …, 2016 - Elsevier
Abstract Background Seven Tesla (7T) MRI can visualize anatomical alterations occurring in
a hyperintense structure of the substantia nigra in Parkinson's disease (PD). Objective We …
a hyperintense structure of the substantia nigra in Parkinson's disease (PD). Objective We …
The 'swallow tail'appearance of the healthy nigrosome–a new accurate test of Parkinson's disease: a case-control and retrospective cross-sectional MRI study at 3T
There is no well-established in vivo marker of nigral degeneration in Parkinson's disease
(PD). An ideal imaging marker would directly mirror the loss of substantia nigra …
(PD). An ideal imaging marker would directly mirror the loss of substantia nigra …
Imaging degeneration of the substantia nigra in Parkinson disease with inversion-recovery MR imaging
L Minati, M Grisoli, F Carella… - American journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Visualizing with MR imaging and obtaining quantitative
indexes of degeneration of the substantia nigra in Parkinson disease have been long …
indexes of degeneration of the substantia nigra in Parkinson disease have been long …
Diffusion tensor imaging of the substantia nigra in P arkinson's disease revisited
J Langley, DE Huddleston, M Merritt… - Human Brain …, 2016 - Wiley Online Library
Objective To analyze diffusion tensor imaging (DTI) data in the substantia nigra (SN) using a
more consistent region of interest (ROI) defined by neuromelanin‐sensitive MRI in order to …
more consistent region of interest (ROI) defined by neuromelanin‐sensitive MRI in order to …