Obesity and diabetes are risk factors for hepatocellular carcinoma (HCC); however, the
underlying mechanisms are yet to be elucidated. Adeno‐associated virus (AAV) frequently …

Abstract Apolipoprotein A5 (apoA5) has been implicated in the formation of hepatocyte lipid
droplets, a histological hallmark of non-alcoholic fatty liver disease (NAFLD). Recent …

Adeno-associated viral (AAV) vectors are widely used in clinical gene therapy and, in
particular, in applications based on in vivo gene transfer. These recombinant vectors are …

Cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is a sequence-specific
RNA-binding protein. We had reported that CPEB3 is involved in hepatocellular carcinoma …

Glycine N-methyltransferase (GNMT) is abundantly expressed in normal livers and plays a
protective role against tumor formation. GNMT depletion leads to progression of …

Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its
complexity necessitates novel strategies for drug selection and design. Current approaches …

Recent clinical successes in gene therapy applications have intensified interest in using
adeno-associated viruses (AAVs) as vectors for therapeutic gene delivery. Although …

Due to the rise in overnutrition, the incidence of obesity-induced hepatocellular carcinoma
(HCC) will continue to escalate; however, our understanding of the obesity to HCC …

Deciphering the crosstalk between RNA-binding proteins and corresponding RNAs will
provide a better understanding of gastric cancer (GC) progression. The comprehensive …

Adeno-associated virus (AAV) vectors are used to deliver therapeutic transgenes, but host
immune responses may interfere with transduction and transgene expression. We evaluated …